Asthma prevalence in 1973, 1988 and 2003
Asthma prevalence in 1973, 1988 and 2003
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DOI：
10.1136/thx.2005.045682
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发表时间：
2006-04-01
期刊：
影响因子：
10
通讯作者：
Doull, IJM
中科院分区：
文献类型：
--
作者：
Burr, ML;Wat, D;Doull, IJM
背景资料：进行了一项研究，以了解自1988年进行一项调查以来，哮喘的患病率是否发生了变化，使用的方法与过去15年中哮喘患病率上升的方法相同。方法：对南威尔士的学校中的12岁儿童进行了调查，该调查于1973年和1988年进行。调查包括家长填写的问卷和运动挑战试验，进行时，没有支气管扩张剂最近used.Results：在1973年，1988年和2003年，问卷分别获得817，965和1148名儿童，分别由812，960和1019名儿童，分别进行了运动试验。在过去的一年中，报告的喘息患病率在每15年期间都在上升（9.8%，15.2%，19.7%），报告的哮喘患病率甚至有史以来上升更快（5.5%，12.0%，27.3%）。在所有儿童（5.8%，10.5%，16.0%）和有喘息病史的儿童（34.1%，47.0%，57.3%）中，跑步导致的喘息持续增加。1988年至2003年，吸入性皮质类固醇（1973年不可用）的使用增加了四倍。运动诱发支气管收缩的患病率在1973年至1988年期间上升，但到2003年有所下降。结论：哮喘症状的患病率自1988年以来持续上升。这似乎与最近报告的下降相矛盾，除非哮喘患病率在20世纪90年代达到顶峰。运动引起的支气管收缩的减少可能是由于更好地控制了疾病，因为更多的儿童现在使用吸入性皮质类固醇作为预防性治疗。
Background: A study was undertaken to see whether the prevalence of asthma has changed since a survey was conducted in 1988, using the same methods that showed an increase during the previous 15 years.Methods: A survey of 12 year old children was conducted in schools in South Wales where surveys had taken place in 1973 and 1988. The survey comprised a parentally completed questionnaire and an exercise challenge test, performed when no bronchodilator had been recently used.Results: In 1973, 1988, and 2003, questionnaires were obtained for 817, 965 and 1148 children, respectively; the exercise test was performed by 812, 960 and 1019 children, respectively. The prevalence of reported wheeze in the last year rose during each 15 year period (9.8%, 15.2%, 19.7%), with an even steeper rise in reported asthma ever (5.5%, 12.0%, 27.3%). There was a continued increase in wheeze attributed to running, in terms of all children (5.8%, 10.5%, 16.0%) and also as the proportion of those with a history of wheeze ( 34.1%, 47.0%, 57.3%). The use of inhaled corticosteroids ( not available in 1973) increased fourfold between 1988 and 2003. The prevalence of exercise induced bronchoconstriction rose between 1973 and 1988 but had declined by 2003.Conclusions: The rise in the prevalence of asthmatic symptoms has continued since 1988. This appears to conflict with a reported recent decline, unless asthma prevalence peaked in the 1990s. The decline in exercise induced bronchoconstriction is probably attributable to better control of the disease as more children are now using inhaled corticosteroids as preventive treatment.