A comparison of photoplethysmography and ECG recording to analyse heart rate variability in healthy subjects
A comparison of photoplethysmography and ECG recording to analyse heart rate variability in healthy subjects
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DOI：
10.3109/03091900903150998
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发表时间：
2009-11-01
影响因子：
--
通讯作者：
Stein, J. F.
中科院分区：
文献类型：
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作者：
Lu, G.;Yang, F.;Stein, J. F.
心率变异性（HRV）被广泛用于评估自主神经系统（ANS）功能。这些信号需要精确地确定连续心跳之间的间隔；它可以通过心电图（ECG）记录，这是一种无创且广泛使用的方法。然而，在ECG记录和分析中固有的方法学问题促使人们寻找替代方案。光容积脉搏波（PPG）是通过连续监测一部分外周微血管的血容量变化来确定心脏周期时间的另一种方法。该技术测量脉冲波形，在某些情况下可以证明HRV分析的实用基础。我们探讨了利用耳垂PPG分析HRV的可行性，将相同的分析过程应用于同时进行的PPG和心电记录。比较5分钟的记录显示，在时域和频域以及从PPG和ECG得出的HRV测量值之间的非线性动态分析中，HRV测量值具有非常高的相关性。我们的研究结果证实，PPG提供了准确的脉间间隔，在理想条件下，健康受试者的HRV测量可以准确地推导出来，这表明该技术可能被证明是HRV分析的实用替代心电图。这一发现与周围运动过度或震颤患者的护理特别相关，这使得指尖PPG记录不切实际，并且在已知的临床干预措施中引入电伪影到心电图中。
Measures of heart rate variability (HRV) are widely used to assess autonomic nervous system (ANS) function. The signal from which they are derived requires accurate determination of the interval between successive heartbeats; it can be recorded via electrocardiography (ECG), which is both non-invasive and widely available. However, methodological problems inherent in the recording and analysis of ECG traces have motivated a search for alternatives. Photoplethysmography (PPG) constitutes another means of determining the timing of cardiac cycles via continuous monitoring of changes in blood volume in a portion of the peripheral microvasculature. This technique measures pulse waveforms, which in some instances may prove a practical basis for HRV analysis. We investigated the feasibility of using earlobe PPG to analyse HRV by applying the same analytic process to PPG and ECG recordings made simultaneously. Comparison of 5-minute recordings demonstrated a very high degree of correlation in the temporal and frequency domains and in nonlinear dynamic analyses between HRV measures derived from PPG and ECG. Our results confirm that PPG provides accurate interpulse intervals from which HRV measures can be accurately derived in healthy subjects under ideal conditions, suggesting this technique may prove a practical alternative to ECG for HRV analysis. This finding is of particular relevance to the care of patients suffering from peripheral hyperkinesia or tremor, which make fingertip PPG recording impractical, and following clinical interventions known to introduce electrical artefacts into the electrocardiogram.