Psychopathy and response inhibition: A meta-analysis of go/no-go and stop signal task performance.

Psychopathy and response inhibition: A meta-analysis of go/no-go and stop signal task performance.
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精神病和反应抑制:进行/不进行和停止信号任务表现的荟萃分析。

DOI:
10.1016/j.neubiorev.2022.104868
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发表时间:
2022
影响因子:
8.2
通讯作者:
Gillespie SM
Gillespie SM
中科院分区:
医学1区
文献类型:
--
作者:
Gillespie SM

文献摘要

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传统的和更现代的精神病概念化引用了冲动控制的问题。然而,这些问题在多大程度上代表了这种疾病的一个主要特征,这一点一直存在争议。在这项研究中,我们进行了一项预先注册的系统综述和荟萃分析,检索了Embase、Medline、PsycINFO和PubMed,以查找从开始到2022年1月6日的研究。我们纳入了2009年至2021年间发表的21项研究,这些研究报告了精神病与去/不去或停止信号任务的关系。一项多水平随机效应荟萃分析,包括来自17项研究(总N = 1394)的43个效应量,显示精神病与反应抑制之间存在显著的合并相关r =-0.143(95%CI:-0.250至-0.034)。虽然在统计学上有显著意义,但相对较小的效应量却让人质疑,在多大程度上,反应抑制的困难应该被视为精神病态人格的一个主要特征。非犯罪和犯罪样本,性别,任务类型,有或没有情感成分的任务,或精神病特质维度之间的关系的强度没有显着差异。
Traditional and more modern conceptualizations of psychopathy cite problems with impulse control. However, the extent to which these problems represent a cardinal feature of the disorder has been debated. In this study, we conducted a preregistered systematic review and meta-analysis, searching Embase, Medline, PsycINFO, and PubMed, for studies from inception to January 6th, 2022. We included 21 studies, published between 2009 and 2021, that reported on the relationship of psychopathy with performance on the go/no-go or stop signal task. A multilevel random-effects meta-analysis, including 43 effect sizes from 17 studies (totalN= 1394), showed a significant pooled association between psychopathy and response inhibitionr= −0.143 (95 % CI: −0.250 to −0.034). The relatively small effect size, although statistically significant, calls in to question the extent to which difficulties in response inhibition should be considered a cardinal feature of psychopathic personality. The strength of the relationship did not significantly differ between non-criminal and criminal samples, gender, task type, tasks with or without an affective component, or by psychopathy trait dimension.