Effect of Yi Gong San Decoction on Iron Homeostasis in a Mouse Model of Acute Inflammation.
Effect of Yi Gong San Decoction on Iron Homeostasis in a Mouse Model of Acute Inflammation.
复制标题
益公散汤对小鼠急性炎症模型铁稳态的影响
DOI：
10.1155/2016/2696480
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发表时间：
2016
期刊：
影响因子：
--
通讯作者：
Luo M
中科院分区：
文献类型：
--
作者：
Zheng Q;Guan Y;Xia L;Wang Z;Jiang Y;Zhang X;Wang J;Wang G;Pu Y;Xia J;Luo M
本研究探讨益宫散对小鼠急性炎症模型铁稳态的影响及其可能的机制。我们的研究结果表明，YGS通过下调HAMP mRNA水平来调节铁稳态，这可能依赖于急性炎症期间对IL-6/STAT3或BMP/HJV/SMAD通路的调节。
We investigated the effect of Yi Gong San (YGS) decoction on iron homeostasis and the possible underlying mechanisms in a mouse model of acute inflammation in this study. Our findings suggest that YGS regulates iron homeostasis by downregulating the level of HAMP mRNA, which may depend on regulation of the IL-6/STAT3 or BMP/HJV/SMAD pathway during acute inflammation.