Redesigning Organ Allocation Boundaries for Liver Transplantation in the United States.
Redesigning Organ Allocation Boundaries for Liver Transplantation in the United States.
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DOI：
10.1007/978-3-319-01848-5_2
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发表时间：
2014
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移植机会和结果的地理差异一直是移植研究人员和移植界广泛讨论的一个持续存在的问题。据称造成美国差异的原因之一是行政上确定的器官分配边界，限制了跨地区的器官共享。本文应用数学编程来构建替代肝脏分配边界，与当前系统相比，在获得移植方面实现更多的地理公平性。使用离散事件模拟评估最佳边界的性能，并将其与当前分配系统的性能进行比较。
Geographic disparities in access to and outcomes in transplantation have been a persistent problem widely discussed by transplant researchers and the transplant community. One of the alleged causes of disparities in the United States is administratively determined organ allocation boundaries that limit organ sharing across regions. This paper applies mathematical programming to construct alternative liver allocation boundaries that achieve more geographic equity in access to transplants than the current system. The performance of the optimal boundaries were evaluated and compared to that of current allocation system using discrete event simulation.