Incidence and Severity of Obstructive Sleep Apnea following Pharyngeal Flap Surgery in Patients with Cleft Palate
Incidence and Severity of Obstructive Sleep Apnea following Pharyngeal Flap Surgery in Patients with Cleft Palate
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腭裂患者咽皮瓣手术后阻塞性睡眠呼吸暂停的发生率和严重程度
DOI：
10.1597/1545-1569_2002_039_0312_iasoos_2.0.co_2
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发表时间：
2002
期刊：
影响因子：
--
通讯作者：
Chiung
中科院分区：
文献类型：
--
作者：
Y. Liao;M. Chuang;P. Chen;N. Chen;C. Yun;Chiung
目的：调查腭裂患者术后至少 6 个月与咽瓣手术相关的阻塞性睡眠呼吸暂停 (OSA) 的发生率和严重程度，并确定年龄或瓣宽度是否对其有影响。本研究检验的假设是，与咽瓣手术相关的 OSA 在儿童中的严重程度高于成人。受试者：10 名成人，6 名男性和 4 名女性，咽瓣平均年龄 28.0 岁（成人组）。儿童28例，男13例，女15例，咽瓣平均年龄6.3岁（儿童组）。设计：前瞻性分析。主要结果指标：采用隔夜多导睡眠图研究来确定咽瓣术后 6 个月 OSA 的发生率和严重程度。结果：咽瓣术后 OSA 的发生率很高，但两组之间无显着差异（成人为 90%，儿童为 93%，p = 5 1.000）。当根据呼吸障碍指数值将 OSA 分为不同严重程度时，两组之间存在显着差异 (p 5 .022)。在成人组中，8 名患者 (89%) 患有轻度 OSA，1 名患者 (11%) 患有中度至重度 OSA。在儿童组中，11 名患者（42%）患有轻度 OSA，15 名患者（58%）患有中重度 OSA。在各组中，皮瓣宽度与 OSA 发生率（成人 p = 5 .435，儿童 p = 0.640）或严重程度（成人 p = 5 .325，儿童 p = 0.310）之间没有相关性。结论：咽瓣手术后6个月，90%以上的腭裂患者仍有OSA。儿童中与咽瓣手术相关的 OSA 的严重程度往往比成人更严重。无论是成人还是儿童，皮瓣宽度与 OSA 的发生率和严重程度无关。
Objective: To investigate the incidence and severity of obstructive sleep apnea (OSA) associated with pharyngeal flap surgery in patients with cleft palate at least 6 months postoperatively and to determine whether age or the flap width had an effect on them. The hypothesis tested in this study was that the severity of OSA associated with pharyngeal flap surgery is greater in children than in adults. Subjects: Ten adults, six men and four women, with a mean age of 28.0 years at pharyngeal flap (adult group). Twenty-eight children, 13 boys and 15 girls, with a mean age of 6.3 years at pharyngeal flap (child group). Design: A prospective analysis. Main Outcome Measures: An overnight polysomnographic study was used to determine the incidence and severity of OSA 6 months after pharyngeal flap. Results: The incidence of OSA following pharyngeal flap was high but not significantly different between these two groups (90% in adults and 93% in children, p 5 1.000). When OSA was stratified into different levels of severity according to the values of respiratory disturbance index, there were noticeable differences between these two groups (p 5 .022). In the adult group, eight patients (89%) had mild OSA and 1 patient (11%) had moderate to severe OSA. In the child group, 11 patients (42%) were found to have mild OSA, and 15 patients (58%) had moderate to severe OSA. No relation was found between the flap width and the incidence (p 5 .435 in adults and .640 in children) or the severity (p 5 .325 in adults and .310 in children) of OSA in each group. Conclusions: Six months following pharyngeal flap surgery, more than 90% of the patients with cleft palate still had OSA. The severity of OSA associated with pharyngeal flap surgery tended to be greater in children than in adults. The flap width was unrelated to the incidence and severity of OSA, no matter in adults or in children.
儿童阻塞性睡眠呼吸暂停的病理生理学：当前概念。
DOI：
10.1016/s0034-5687(99)00109-7
发表时间：
2000
期刊：
Respiration physiology
影响因子：
--
作者：
Marcus,CL
通讯作者：
Marcus,CL
DOI：
10.1164/ajrccm/146.5_pt_1.1235
发表时间：
1992-11-01
期刊：
AMERICAN REVIEW OF RESPIRATORY DISEASE
影响因子：
--
作者：
MARCUS, CL;OMLIN, KJ;WARD, SLD
通讯作者：
WARD, SLD
DOI：
--
发表时间：
1986
期刊：
The Cleft palate journal
影响因子：
--
作者：
VanDemark,DR;Hardin,MA
通讯作者：
Hardin,MA