Classified status of smoking and quitting has different associations with dyslipidemia in residents in northeast China.
Classified status of smoking and quitting has different associations with dyslipidemia in residents in northeast China.
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DOI：
10.1016/j.cca.2018.08.001
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发表时间：
2018-11
期刊：
影响因子：
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通讯作者：
Jikang Shi;Ye Bai;Shuang Qiu;Yong Li;C. Kou;Y. Tao;Qing Zhen;Yulu Gu;Yaqin Yu;Kaixin Zhang;Yi Cheng;Yawen Liu
中科院分区：
文献类型：
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作者：
Jikang Shi;Ye Bai;Shuang Qiu;Yong Li;C. Kou;Y. Tao;Qing Zhen;Yulu Gu;Yaqin Yu;Kaixin Zhang;Yi Cheng;Yawen Liu
研究背景东北地区居民吸烟状况不一，血脂异常患病率高。然而，血脂异常与吸烟状态的关联尚不清楚。MethodsA共17，114名参与者选择了一个多阶段分层整群随机抽样设计，从中国东北地区进行的横断面研究。血脂异常与吸烟/戒烟状态（吸烟量，吸烟时间，戒烟时间）的协会进行了调查，采用多元Logistic regulation.ResultsPrevalence（39.2%）血脂异常存在于中国东北地区的居民。吸烟量与血脂异常相关（每日1-10支：OR= 1.19，95%CI：1.08-1.32;每日11-20支：OR= 1.29，95%CI：1.16-1.42;每日20支以上：OR= 1.51，95%CI：1.25-1.83）。吸烟时间与血脂异常风险相关（6-10年：OR= 1.75，95%CI：1.51-2.03; 11-15年：OR= 1.85，95%CI：1.51-2.26; ≥15年：OR= 1.12，95%CI：1.02-1.23）。戒烟时间（1-5年）与血脂异常相关（OR= 1.26，95%CI：1.07-1.48）;然而，我们发现血脂异常与戒烟时间（超过6年）之间无统计学显著相关性。吸烟量和吸烟时间可能共同决定血脂异常风险，戒烟时间（>6年）是降低血脂异常风险的必要条件。
BackgroundVarious smoking status and high prevalence of dyslipidemia in residents exist in northeast China. However, associations of dyslipidemia with smoking status remain unclear.MethodsA total of 17,114 participants selected by a multistage stratified cluster random sampling design were enrolled from a cross-sectional study conducted in northeast China. Associations of dyslipidemia with smoking/quitting status (smoking amount, smoking duration, and quitting duration) were investigated using multiple logistic regression.ResultsPrevalence (39.2%) of dyslipidemia existed in residents in northeast China. Smoking amount was associated with dyslipidemia (1–10 cigarettes daily:OR= 1.19, 95%CI: 1.08–1.32; 11–20 cigarettes daily:OR= 1.29, 95%CI: 1.16–1.42; and over 20 cigarettes daily:OR= 1.51, 95%CI: 1.25–1.83). Smoking duration was associated with dyslipidemia risk (6–10 years:OR= 1.75, 95%CI: 1.51–2.03; 11–15 years:OR= 1.85, 95%CI: 1.51–2.26; and ≥15 years:OR= 1.12, 95%CI: 1.02–1.23). Quitting duration (1–5 years) was associated with dyslipidemia (OR= 1.26, 95%CI: 1.07–1.48); however, we found no statistically significant associations between dyslipidemia and quitting duration (over 6 years).ConclusionsDyslipidemia risk is positively associated with smoking/quitting status. Smoking amount and smoking duration may co-determine dyslipidemia risk, and quitting duration (>6 years) is necessary for reducing dyslipidemia risk.