A new cycloaddition profile for <i>ortho</i>-quinone methides: photoredox-catalyzed [6+4] cycloadditions for synthesis of benzo[<i>b</i>]cyclopenta[<i>e</i>]oxepines
A new cycloaddition profile for <i>ortho</i>-quinone methides: photoredox-catalyzed [6+4] cycloadditions for synthesis of benzo[<i>b</i>]cyclopenta[<i>e</i>]oxepines
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邻醌甲基化物的新环加成谱：光氧化还原催化的[6 4]环加成合成苯并[<i>b</i>]环戊[<i>e</i>]
DOI：
10.1039/d1cc06332d
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发表时间：
2022
影响因子：
4.9
通讯作者：
Hoshino Yujiro
中科院分区：
文献类型：
--
作者：
Tanaka Kenta;Asada Yosuke;Hoshino Yujiro
研究了邻醌类化合物的可见光诱导[6+4]环加成反应。邻醌类化合物在硫代蒽醌光氧化还原催化剂的作用下与五氟烯发生反应，得到苯并[b]环五[e]氧平。目前的反应为合成含有苯并西平结构的天然产物和生物活性化合物提供了一个很有前途的工具。
Visible-light-induced [6+4] cycloaddition reactions of ortho-quinone methides have been developed. The reaction of ortho-quinone methides with pentafulvenes in the presence of a thioxanthylium photoredox catalyst afforded benzo[b]cyclopenta[e]oxepines. The present reaction represents a promising tool for the synthesis of natural products and bioactive compounds that contain a benzoxepine structure.