Discovering drugs to treat coronavirus disease 2019 (COVID-19)

Discovering drugs to treat coronavirus disease 2019 (COVID-19)
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DOI:
10.5582/ddt.2020.01012
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发表时间:
2020-02-01
影响因子:
3.1
通讯作者:
Gao, Jianjun
Gao, Jianjun
中科院分区:
其他
文献类型:
--
作者:
Dong, Liying;Hu, Shasha;Gao, Jianjun

文献摘要

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SARS-CoV-2病毒于2019年12月出现,随后在全球范围内迅速传播,特别是向中国、日本和韩国传播。科学家们正在努力寻找针对该病毒的抗病毒药物。氯喹、阿比多尔、瑞美西韦、法韦拉韦等几种药物目前正在进行临床研究,以测试它们在中国治疗冠状病毒病2019年(新冠肺炎)的疗效和安全性;目前已取得一些可喜的结果。本文综述了对SARS-CoV-2有潜在疗效的药物。
The SARS-CoV-2 virus emerged in December 2019 and then spread rapidly worldwide, particularly to China, Japan, and South Korea. Scientists are endeavoring to find antivirals specific to the virus. Several drugs such as chloroquine, arbidol, remdesivir, and favipiravir are currently undergoing clinical studies to test their efficacy and safety in the treatment of coronavirus disease 2019 (COVID-19) in China; some promising results have been achieved thus far. This article summarizes agents with potential efficacy against SARS-CoV-2.