Incidence of cardiac arrhythmias with therapeutic versus diagnostic ultrasound and intravenous microbubbles
Incidence of cardiac arrhythmias with therapeutic versus diagnostic ultrasound and intravenous microbubbles
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DOI：
10.7863/jum.2005.24.8.1099
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发表时间：
2005-08-01
影响因子：
2.3
通讯作者：
Porter, TR
中科院分区：
文献类型：
--
作者：
Chapman, S;Windle, J;Porter, TR
Objective.本研究的目的是确定在存在静脉微泡的情况下，治疗性与诊断性经胸低频超声（TLFUS）换能器诱导的心律失常类型。方法.静脉内全氟化碳暴露的超声葡萄糖白蛋白（PESDA）微泡输注或作为团注给予，而TLFUS应用于标准胸骨旁和心尖视图，使用1 MHz治疗超声换能器或高机械指数诊断超声（11.7 MHz）。结果治疗换能器产生的异位明显更多，尤其是在PESDA团注后连续波模式下的高强度设置下（P
Objective. The purpose of this study was to determine the type of arrhythmias induced with therapeutic versus diagnostic transthoracic low-frequency ultrasound (TLFUS) transducers in the presence of intravenous microbubbles. Methods. Intravenous perfluorocarbon-exposed sonicated dextrose albumin (PESDA) microbubbles were infused or given as a bolus injection while TLFUS was applied in the standard parasternal and apical views with either a 1-MHz therapeutic ultrasound transducer or high-mechanical-index diagnostic ultrasound (11.7 MHz). Results. Significantly more ectopy was produced by the therapeutic transducer, especially at higher-intensity settings in the continuous wave mode after bolus injections of PESDA (P