Usefulness of a cube-copying test in outpatients with dementia
Usefulness of a cube-copying test in outpatients with dementia
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DOI：
10.1080/02699050410001671847
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发表时间：
2004-09-01
期刊：
影响因子：
1.9
通讯作者：
Moriwaki, H
中科院分区：
文献类型：
--
作者：
Maeshima, S;Osawa, A;Moriwaki, H
目的：阐明定量评分的立方体复制测试是否可以快速评估痴呆患者，预测他们在认知测试中的表现。方法：受试者为 171 名门诊失忆症患者，其中 92 名患有阿尔茨海默病（AD）； 59 血管性痴呆（VD）； 17 额颞叶痴呆（FTD）；以及 3 名路易体病 (DLB) 和 32 名正常健康受试者。受试者被要求复制一个立方体的透视图。使用前岛方法对连接点和平面方向误差进行评分。进行了简易精神状态检查（MMSE）、听觉言语学习测试（AVLT）、单词流利度测试和瑞文彩色渐进矩阵（RCPM）。评估年龄、临床疾病严重程度、症状持续时间、具体诊断和神经心理学评分与构建能力的关系。结果：立方体复制测试在大多数痴呆症患者和 32 名正常受试者中的 11 名中显示错误。只有 3 名患有 AD 和 VD 的患者正确复制了立方体，但 11 名患有 17 FTD 的患者正确绘制了立方体。完成的连接数量和平面方向错误与 MMSE、AVLT、词语流利度和 RCPM 分数显着相关。 结论：立方体复制测试对于常规临床痴呆筛查很有用，但该测试仅检查认知功能的一方面。虽然不能替代传统的神经心理学检查，但定量评分的立方体复制可以提供痴呆患者认知功能障碍的粗略估计。
Objective: To clarify whether a quantitatively scored cube-copying test could rapidly assess dementia patients, predicting thier performance in cognitive tests.Methods: Subjects were 171 outpatients with amnesia who were including 92 with Alzheimer's disease (AD); 59 vascular dementia (VD); 17 frontotemporal dementia (FTD); and three lewy body disease (DLB) and 32 normal healthy subjects. Subjects asked to copy a perspective drawing of a cube. Points of connection and plane-orientation errors were scored using Maeshima's method. The Mini-Mental State Examination (MMSE), an auditory verbal learning test (AVLT), a word fluency test and Raven's Coloured Progressive Matrices (RCPM) were administered. Age, clinical disease severity, symptom duration, specific diagnosis and neuropsychological scores were evaluated for relationships with constructional ability.Results: The cube-copying test showed errors in most dementia patients and 11 of 32 normal subjects. Only three patients each with AD and VD copied correctly, but 11 patients with 17 FTD drew the cube correctly. Numbers of connections completed and plane-orientation errors correlated significantly with MMSE, AVLT, word fluency and RCPM scores.Conclusion: The cube-copying test is useful for routine clinical dementia screening, however the test examines only one aspect of cognitive function. While not an alternative to conventional neuropsychological examinations, quantitatively scored cube copying can provide a rough estimate of cognitive dysfunction in dementia patients.