Sasang Constitutional Medicine as a Holistic Tailored Medicine
Sasang Constitutional Medicine as a Holistic Tailored Medicine
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DOI：
10.1093/ecam/nep100
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发表时间：
2009-09-01
影响因子：
--
通讯作者：
Duong Duc Pham
中科院分区：
文献类型：
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作者：
Kim, Jong Yeol;Duong Duc Pham
Sasang体质医学（SCM）是一种独特的韩国传统治疗替代医学形式。根据阴阳学说和儒家思想，人分为四种体质。这些差异在于（i）对某些草药和药物的敏感性，（ii）内部器官功能之间的平衡，（iii）身体特征和（iv）心理特征。我们提出SCM的两个主要病理生理学轴（食入/废物排出和消耗/储存气和体液）分别相当于现代生理学中的内外交换和排泄/排泄过程。然后，我们用这个假设来讨论SCM的生理和病理原理。体质医学的理论基础是，一些草药和补救措施只适用于某些体质，并可能对其他体质造成不良影响。SCM的宪法方法与定制医学有着相同的愿景;个体化治疗，可以最大限度地减少不良反应的风险，同时提高疗效和个体化自我调节，可以帮助预防特定的易感慢性疾病，健康生活。对于SCM和定制医学来说，实现这一目标还有很长的路要走，但我们可以从系统生物学等系统方法中受益。我们认为，SCM的宪法的角度和我们的假设的两个主要过程可能会提供一个新的见解，为进一步的研究。
Sasang constitutional medicine (SCM) is a unique traditional Korean therapeutic alternative form of medicine. Based on the Yin and Yang theory and on Confucianism, humans are classified into four constitutions. These differ in terms of (i) sensitivity to certain groups of herbs and medicines, (ii) equilibrium among internal organic functions, (iii) physical features and (iv) psychological characteristics. We propose that two main axes in the physiopathology of SCM (food intake/waste discharge and consuming/storing Qi and body fluids) are equivalent to the process of internal-external exchange and catabolism/anabolism in modern physiology, respectively. We then used this hypothesis to discuss the physiological and pathological principles of SCM. Constitution-based medicine is based on the theory that some medicinal herbs and remedies are only appropriate for certain constitutions and can cause adverse effects in others. The constitutional approach of SCM share the same vision as tailored medicine; an individualized therapy that can minimize the risk of adverse reaction while increasing the efficacy and an individualized self-regulation that can help prevent specific susceptible chronic disease and live healthily. There is still a long way to this goal for both SCM and tailored medicine, but we may benefit from systems approaches such as systems biology. We suggest that constitutional perspective of SCM and our hypothesis of two main processes may provide a novel insight for further studies.