Spatial variability of climate effects on ischemic heart disease hospitalization rates for the period 1989-2006 in Quebec, Canada.

Spatial variability of climate effects on ischemic heart disease hospitalization rates for the period 1989-2006 in Quebec, Canada.
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DOI:
10.1186/1476-072x-9-5
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发表时间:
2010-02-08
影响因子:
4.9
通讯作者:
Chebana F
Chebana F
中科院分区:
医学3区
文献类型:
--
作者:
Bayentin L;El Adlouni S;Ouarda TB;Gosselin P;Doyon B;Chebana F

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研究表明,气候变量和循环系统疾病之间存在关联。对魁北克18个健康地区1989-2006年期间气候条件对缺血性心脏病(IHD)发病率的短期影响进行了研究。对两个年龄组进行了分析。GAM统计模型融合了广义线性模型和加性模型的性质,用于拟合IHD的标准化每日住院率及其与入院前两周气候条件的关系,控制了时间趋势、季节日期和性别。结果表明,在魁北克的大部分地区,冬季的寒冷和夏季的炎热与IHD的每日住院率增加高达12%有关,但在一些地区也显示出风险降低。年龄在45岁-之间的男性和女性住院的风险更高,而且在空间上存在差异。在大多数地区,连续一段时间的寒冷或高温比只有一天的极端天气更有害。年龄在45-之间的男性患IHD的风险水平高于同年龄段的女性。在大多数地区,与较年轻的年龄组相比,65岁的人在本季度早些时候达到了每年65岁的IHD入院人数上限,无论是性别还是两个季节。气象变量对每日IHD住院率的影响在吸烟率高和剥夺指数高的地区更为明显。这项研究强调了魁北克健康地区寒冷和炎热时期对IHD的不同影响,这取决于年龄、性别和其他因素,如吸烟、行为和剥夺程度。
Studies have suggested an association between climate variables and circulatory diseases. The short-term effect of climate conditions on the incidence of ischemic heart disease (IHD) over the 1989-2006 period was examined for Quebec's 18 health regions. Analyses were carried out for two age groups. A GAM statistical model, that blends the properties of generalized linear models with additive models, was used to fit the standardized daily hospitalization rates for IHD and their relationship with climatic conditions up to two weeks prior to the day of admission, controlling for time trends, day of the season and gender. Results show that, in most of Quebec's regions, cold temperatures during winter months and hot episodes during the summer months are associated with an increase of up to 12% in the daily hospital admission rate for IHD but also show decreased risks in some areas. The risk of hospitalization is higher for men and women of 45-64 years and varies spatially. In most regions, exposure to a continuous period of cold or hot temperature was more harmful than just one isolated day of extreme weather. Men aged 45-64 years showed higher risk levels of IHD than women of the same age group. In most regions, the annual maximum of daily IHD admissions for 65 years old was reached earlier in the season for both genders and both seasons compared to younger age groups. The effects of meteorological variables on the daily IHD admissions rate were more pronounced in regions with high smoking prevalence and high deprivation index. This study highlights the differential effects of cold and hot periods on IHD in Quebec health regions depending on age, sex, and other factors such as smoking, behaviour and deprivation levels.