Agreement between calcaneal quantitative ultrasound and osteoporosis self-assessment tool for Asians in identifying individuals at risk of osteoporosis.
Agreement between calcaneal quantitative ultrasound and osteoporosis self-assessment tool for Asians in identifying individuals at risk of osteoporosis.
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DOI：
10.2147/tcrm.s145519
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发表时间：
2017
影响因子：
2.8
通讯作者：
Soelaiman IN
中科院分区：
文献类型：
--
作者：
Chin KY;Low NY;Kamaruddin AAA;Dewiputri WI;Soelaiman IN
跟骨定量超声（QUS）是一种有用的工具，在骨质疏松症筛查。然而，QUS设备可能并不适用于所有初级卫生保健机构。亚洲人骨质疏松自我评估工具（OSTA）是一种简单的骨质疏松筛查算法，不需要任何复杂的仪器。本研究通过确定OSTA与QUS在识别骨质疏松症风险个体方面的一致性，探讨了OSTA替代QUS的可能性。进行了一项横断面研究，招募了年龄≥50岁的马来西亚男性和女性。使用跟骨QUS设备和OSTA测量他们的骨骼健康状况。使用斯皮尔曼相关性确定OSTA和QUS之间的相关性，并使用Cohen Kappa和受试者工作曲线评估其一致性。所有QUS指标与OSTA显著相关（p<0.05）。QUS和OSTA之间的一致性很小，但具有统计学显著性（p<0.05）。根据QUS，OSTA在识别骨质疏松症风险受试者方面的表现在女性中为较差至中等（p<0.05），但在男性中无统计学意义（p>0.05）。改变截止值可以改善女性OSTA的表现，但对男性没有影响。QUS和OSTA之间的协议是在骨质疏松症的风险分类的个人最小。因此，它们不能在骨质疏松症筛查中互换使用。
Calcaneal quantitative ultrasound (QUS) is a useful tool in osteoporosis screening. However, QUS device may not be available at all primary health care settings. Osteoporosis self-assessment tool for Asians (OSTA) is a simple algorithm for osteoporosis screening that does not require any sophisticated instruments. This study explored the possibility of replacing QUS with OSTA by determining their agreement in identifying individuals at risk of osteoporosis. A cross-sectional study was conducted to recruit Malaysian men and women aged ≥50 years. Their bone health status was measured using a calcaneal QUS device and OSTA. The association between OSTA and QUS was determined using Spearman’s correlation and their agreement was assessed using Cohen Kappa and receiver-operating curve. All QUS indices correlated significantly with OSTA (p<0.05). The agreement between QUS and OSTA was minimal but statistically significant (p<0.05). The performance of OSTA in identifying subjects at risk of osteoporosis according to QUS was poor-to-fair in women (p<0.05), but not statistically significant for men (p>0.05). Changing the cut-off values improved the performance of OSTA in women but not in men. The agreement between QUS and OSTA is minimal in categorizing individuals at risk of osteoporosis. Therefore, they cannot be used interchangeably in osteoporosis screening.