Prospects for organ preservation by vitrification

Prospects for organ preservation by vitrification
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器官玻璃化保存的前景

DOI:
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发表时间:
1982
期刊:
影响因子:
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通讯作者:
A. Hirsch
A. Hirsch
中科院分区:
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文献类型:
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作者:
G. Fahy;A. Hirsch

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虽然大多数有组织的组织和细胞类型可以用相对简单的技术成功冷冻,但心脏、肝脏和肾脏到目前为止都无法在−80°C下冷冻存活。冷冻和解冻引发了无数复杂的、同时发生的破坏性事件,而处理这些事件是一个让大多数器官保护者望而却步的问题。然而,有一种替代方法可以无限期地低温储存器官。
Although most organized tissues and cell types can be successfully frozen with relatively simple techniques, the heart, the liver, and the kidney have so far uniformly failed to survive freezing to −80 °C. Freezing and thawing set into motion a myriad of complex, simultaneous destructive events, and dealing with these events is a problem which has daunted most organ preservationists. There is, however, an alternative approach to indefinite low-temperature banking of organs.