Bacteriophages of spirochetes.
Bacteriophages of spirochetes.
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DOI：
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发表时间：
2000-09
影响因子：
1.2
通讯作者：
Christian H. Eggers;S. Casjens;S. F. Hayes;C. Garon;C. J. Damman;C. J. Damman;D. Oliver;D. Samuels
中科院分区：
文献类型：
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作者：
Christian H. Eggers;S. Casjens;S. F. Hayes;C. Garon;C. J. Damman;C. J. Damman;D. Oliver;D. Samuels
历史上，人们观察到许多噬菌体样颗粒与螺旋体目（螺旋体）的成员有关。在过去的十年中，已经在分子水平上分离和表征了几种螺旋体噬菌体。我们最近鉴定了莱姆病病原体伯氏疏螺旋体的噬菌体，我们将其命名为 phiBB-1。在这里，我们回顾了螺旋体与其噬菌体之间的关联历史，特别强调 phiBB-1 及其原噬菌体，即伯氏疏螺旋体的 32 kb 环形质粒家族。
Historically, a number of bacteriophage-like particles have been observed in association with members of the bacterial order Spirochetales, the spirochetes. In the last decade, several spirochete bacteriophages have been isolated and characterized at the molecular level. We have recently characterized a bacteriophage of the Lyme disease agent, Borrelia burgdorferi, which we have designated phiBB-1. Here we review the history of the association between the spirochetes and their bacteriophages, with a particular emphasis on phiBB-1 and its prophage, the 32-kb circular plasmid family of B. burgdorferi.