Bad news: The influence of news coverage and Google searches on Gardasil adverse event reporting
Bad news: The influence of news coverage and Google searches on Gardasil adverse event reporting
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DOI：
10.1016/j.vaccine.2017.10.004
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发表时间：
2017-12-14
期刊：
影响因子：
5.5
通讯作者：
Martin, Leslie R.
中科院分区：
文献类型：
--
作者：
Faasse, Kate;Porsius, Jarry T.;Martin, Leslie R.
背景：人乳头瘤病毒疫苗是一种安全有效的工具，可以减少HPV感染，可导致宫颈癌。然而，由于许多人持有消极的信念和误解，这些疫苗的吸收情况并不理想。这种信念与医疗后令人不快的副作用的经历有关，媒体的报道可能会加剧这种担忧。方法：本研究旨在评估新闻报道（每月新闻文章数量）对新西兰7.5年期间Gardasil疫苗接种不良事件报告的影响，以及新闻报道的影响是否受互联网搜索活动（谷歌搜索量）的介导。采用多元线性回归分析和简单中介分析，控制接种疫苗的年份和数量。结果：在考虑疫苗接种率和年份后，上个月的新闻报道和同月的谷歌搜索量是不良事件报告的重要预测因子。并发谷歌搜索量部分介导了先前新闻报道的影响。结论：结果表明，报道的一些不良事件与疫苗接种本身无关，而是与新闻报道和互联网搜索量有关，这可能导致公众担心潜在的不愉快或有害的结果。这些发现表明心理和社会因素在不良事件报告中的重要性，以及新闻媒体在传播健康信息方面的作用。(c) 2017 Elsevier Ltd.版权所有。
Background: Human papilloma virus vaccines are a safe and effective tool for reducing HPV infections that can cause cervical cancer. However, uptake of these vaccines has been suboptimal, with many people holding negative beliefs and misconceptions. Such beliefs have been linked with the experience of unpleasant side effects following medical treatment, and media coverage may heighten such concerns.Methods: The present study sought to assess the influence of news coverage (number of news articles per month) on adverse event reporting in response to Gardasil vaccination in New Zealand over a 7.5-year period, and whether the influence of news coverage was mediated by internet search activity (Google search volumes). Multiple linear regression analyses and simple mediation analyses were used, controlling for year and number of vaccinations delivered.Results: News coverage in the previous month, and Google search volumes in the same month, were significant predictors of adverse event reporting, after accounting for vaccination rates and year. Concurrent Google search volumes partially mediated the effect of prior news coverage.Conclusion: The results suggest that some of the adverse events reported were not related to the vaccination itself, but to news coverage and internet search volumes, which may have contributed to public concerns about potentially unpleasant or harmful outcomes. These findings have implications for the importance of psychological and social factors in adverse event reporting, and the role of the news media in disseminating health information. (c) 2017 Elsevier Ltd. All rights reserved.