Elevated emotion reactivity and emotion regulation in individuals at clinical high risk for developing psychosis and those diagnosed with a psychotic disorder.
Elevated emotion reactivity and emotion regulation in individuals at clinical high risk for developing psychosis and those diagnosed with a psychotic disorder.
复制标题
在临床上发展为精神病的高风险个体和诊断为精神障碍的个体中，情绪反应性和情绪调节升高。
DOI：
10.1111/eip.13212
复制
发表时间：
2022-07
影响因子：
2
通讯作者：
Jalbrzikowski, Maria
中科院分区：
文献类型：
--
作者：
Vines, Leah;Bridgwater, Miranda;Bachman, Peter;Hayes, Rebecca;Catalano, Sabrina;Jalbrzikowski, Maria
情感过程中断是精神病的核心特征，但情绪反应性和情绪调节障碍尚未在临床高风险发展为精神病（Psychosis，简称Psychosis）或诊断为精神障碍（Psychotic Disorder，简称AOP）的青少年中得到充分表征。表征这些损伤可以提供对精神病风险和精神病发作的因素的更全面的理解。使用横截面和纵向数据，我们评估了（1）情绪反应和调节的组水平效应，（2）随时间和年龄的组水平效应的稳定性，（3）情绪反应和调节之间的关系，以及（4）这些措施与心理社会功能和临床病理学之间的关联。87名参与者（年龄12-25岁，TD = 42，AOP = 13; 1-5次访问）完成了情绪反应量表，情绪调节困难量表和情绪调节问卷。我们用前驱综合征结构化访谈评估精神病症状，并用整体功能：社会和角色量表测量现实世界的功能。我们使用方差分析来评估目标1和线性混合模型来解决目标2-4。与TD相比，ESTA和AOP支持经历更高水平的情绪反应和更大的困难利用情绪调节策略。这些损伤在整个时间和青少年发育过程中是稳定的。更高水平的情绪反应与更大的情绪调节障碍有关。情绪调节障碍越严重，社会功能越差，消极症状越严重。旨在减少情绪反应和提高一个人的能力，利用情绪调节策略的治疗干预措施可能是有效的，减少临床神经病学和改善现实世界中的功能，在抑郁症和AOP。
Disrupted affective processes are core features of psychosis; yet emotion reactivity and emotion regulation impairments have not been fully characterized in individuals at clinical high-risk for developing psychosis (CHR) or adolescents diagnosed with a psychotic disorder (AOP). Characterizing these impairments may provide a fuller understanding of factors contributing to psychosis risk and psychosis onset. Using cross-sectional and longitudinal data, we evaluated (1) group-level effects of emotion reactivity and regulation, (2) stability of group-level effects over time and age, (3) relationships between emotion reactivity and regulation, and (4) associations between these measures and psychosocial functioning and clinical symptomatology. Eighty-seven participants (CHR = 32, TD = 42, AOP = 13; 12–25 years, 1–5 visits) completed the Emotion Reactivity Scale, Difficulties in Emotion Regulation Scale, and Emotion Regulation Questionnaire. We assessed psychotic symptoms with the Structured Interview for Prodromal Syndromes and measured real-world functioning with the Global Functioning: Social and Role Scales. We used analysis of variance to assess Aim 1 and linear mixed models to address Aims 2–4. CHR and AOP endorsed experiencing heightened levels of emotion reactivity and greater difficulty utilizing emotion regulation strategies compared to TD. These impairments were stable across time and adolescent development. Greater levels of emotion reactivity were associated with greater emotion regulation impairments. Greater impairments in emotion regulation were associated with lower social functioning and greater negative symptom severity. Therapeutic interventions designed to reduce emotion reactivity and improve one’s ability to utilize emotion regulation strategies may be effective in reducing clinical symptomatology and improving real-world functioning in CHR and AOP.
登录
查看更多内容
影响因子：
4.4
作者：
Fox, H. C.;Hong, K. A.;Sinha, R.
通讯作者：
Sinha, R.
影响因子：
6.6
作者：
Booij, Sanne H.;Snippe, Evelien;Wigman, Johanna T. W.
通讯作者：
Wigman, Johanna T. W.
影响因子：
11.3
作者：
Badcock, Johanna C.;Paulik, Georgie;Maybery, Murray T.
通讯作者：
Maybery, Murray T.
影响因子：
10.3
作者：
Bardeen, Joseph R.;Fergus, Thomas A.
通讯作者：
Fergus, Thomas A.
情绪识别缺陷是精神分裂症临床高风险的个体过渡的预测因素：神经发育的观点。
影响因子：
6.9
作者：
Corcoran, C. M.;Keilp, J. G.;Kayser, J.;Klim, C.;Butler, P. D.;Bruder, G. E.;Gur, R. C.;Javitt, D. C.
通讯作者：
Javitt, D. C.