Early-stage lung adenocarcinomas with a micropapillary pattern, a distinct pathologic marker for a significantly poor prognosis
Early-stage lung adenocarcinomas with a micropapillary pattern, a distinct pathologic marker for a significantly poor prognosis
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DOI：
10.1097/00000478-200301000-00011
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发表时间：
2003-01-01
影响因子：
5.6
通讯作者：
Ishikawa, Y
中科院分区：
文献类型：
--
作者：
Miyoshi, T;Satoh, Y;Ishikawa, Y
微乳头状腺癌（MPP）表现为小的乳头状簇，缺乏中心纤维血管核心，被认为预后较差。为了检验MPP是否是预后的预测因子，我们分析了腺癌的临床病理特征，并特别参考了早期患者的生存。研究对象为1986-1995年间在日本癌症研究所医院接受完整手术切除的连续344例患者（男女比例163:181）。组织学上分为两组：mpp阳性（n = 139, 40%）和mpp阴性（n = 205, 60%）。以下项目在mpp阳性组中更常见：淋巴结转移(p
Adenocarcinomas with a micropapillary pattern (MPP), featuring small papillary tufts lacking a central fibrovascular core, are thought to have a poor prognosis. To examine whether the MPP is a predictor of prognosis, clinicopathologic characteristics of adenocarcinomas were analyzed with particular reference to survival of early-stage patients. The subjects were 344 consecutive patients (female/male ratio 163:181) for whom complete surgical resection was undertaken at the Cancer Institute Hospital, Japan, during 1986-1995. Histologically, they were divided into two groups: MPP-positive (n = 139; 40%) and MPP-negative (n = 205; 60%). The following items were significantly more frequent in the MPP-positive group: metastasis to lymph nodes (p