Cortical auditory processing in preterm newborns: An ERP study

Cortical auditory processing in preterm newborns: An ERP study
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DOI:
10.1016/j.biopsycho.2009.07.005
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发表时间:
2009-10-01
影响因子:
2.6
通讯作者:
Suppiej, Agnese
Suppiej, Agnese
中科院分区:
医学3区
文献类型:
--
作者:
Bisiacchi, Patrizia Silvia;Mento, Giovanni;Suppiej, Agnese

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本研究旨在探讨胎龄对极低胎龄(23-29周,N=20)和低胎龄(30-34周,N=19)早产儿听觉事件相关电位(AERP)的影响。所有受试者在同样的受孕后年龄35周进行测试。使用了一种奇怪的听觉范式,在1000赫兹时出现频繁的“标准”音调,而在2000赫兹时很少出现“异常”音调。小于30周的新生儿的AERPs反应(P1i、N2i和错配反应)较大的新生儿小。我们的结果表明,胎龄是解释这个早期大脑皮质功能的主要因素。(C)2009爱思唯尔B.V.保留所有权利。
The aim of this study was to investigate the effects of gestational age on the auditory event-related potentials (AERPs) in preterm newborns of extremely low (23-29 weeks, N = 20) and low gestational age (30-34 weeks, N = 19). All subjects were tested at the same post-conceptional age of 35 weeks. An auditory oddball paradigm was used with frequently occurring "standard" tones at 1000 Hz and rarely occurring "deviant" tones at 2000 Hz. Newborns of less than 30 gestational weeks showed smaller AERPs responses (P1i, N2i and mismatch response) than the older ones. Our results suggest the role of gestational age as the main factor explaining cortical functioning at this early age. (C) 2009 Elsevier B.V. All rights reserved.