BSR guideline on the management of adults with systemic lupus erythematosus (SLE) 2018: baseline multi-centre audit in the UK
BSR guideline on the management of adults with systemic lupus erythematosus (SLE) 2018: baseline multi-centre audit in the UK
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DOI：
10.1093/rheumatology/keaa759
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发表时间：
2021-03-01
期刊：
影响因子：
5.5
通讯作者：
Lanyon, Peter C.
中科院分区：
文献类型：
--
作者：
Pearce, Fiona A.;Rutter, Megan;Lanyon, Peter C.
目标。为了评估在英国风湿病科就诊的SLE患者的基线护理，根据最近发布的成人SLE管理BSR指南、NICE对贝利单抗的技术评估和英国NHS对利妥昔单抗的临床委托政策的标准进行审核。回顾性审核2018年2月至6月期间任何4周内就诊门诊的SLE病例，以评估之前就诊的护理。临床环境的影响（普通与专门的CTD/血管炎诊所和专业与非专业中心）进行了测试。在显著性水平上应用Bonferroni校正。51个单位参与。我们审核了1003例患者的1021次护理（中位年龄48岁，74%在5年前诊断为bb0）。尽管疾病持续时间较长，但仍有286例（28.5%）患者存在活动性疾病。总的来说，在497（49%）门诊就诊中，记录患者正在接受强的松龙治疗，其中28.5%的就诊被评估为非活动性疾病。低文件合规性(
Objectives. To assess the baseline care provided to patients with SLE attending UK Rheumatology units, audited against standards derived from the recently published BSR guideline for the management of adults with SLE, the NICE technology appraisal for belimumab, and NHS England's clinical commissioning policy for rituximab.Methods. SLE cases attending outpatient clinics during any 4-week period between February and June 2018 were retrospectively audited to assess care at the preceding visit. The effect of clinical environment (general vs dedicated CTD/vasculitis clinic and specialized vs non-specialized centre) were tested. Bonferroni's correction was applied to the significance level.Results. Fifty-one units participated. We audited 1021 episodes of care in 1003 patients (median age 48 years, 74% diagnosed >5 years ago). Despite this disease duration, 286 (28.5%) patients had active disease. Overall in 497 (49%) clinic visits, it was recorded that the patient was receiving prednisolone, including in 28.5% of visits where disease was assessed as inactive. Low documented compliance (