Semiflexible chain networks formed via self-assembly of β-hairpin molecules -: art. no. 268106
Semiflexible chain networks formed via self-assembly of β-hairpin molecules -: art. no. 268106
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DOI：
10.1103/physrevlett.93.268106
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发表时间：
2004-12-31
影响因子：
8.6
通讯作者：
Pochan, DJ
中科院分区：
文献类型：
--
作者：
Ozbas, B;Rajagopal, K;Pochan, DJ
我们报道了从头设计的寡肽的实验结果，该寡肽在分子内折叠事件后分子间自组装成刚性水凝胶网络。显微镜和中子散射显示了直径约3纳米、长度超过数百纳米的纤丝局部结构。振荡流变学表明，多肽网络的粘弹性行为与理论上预测的高度交联的半柔性聚合物网络的粘弹性行为一致。
We report experimental results from a de novo designed oligopeptide that intermolecularly self-assembles into rigid hydrogel networks after an intramolecular folding event. Microscopy and neutron scattering reveal a fibril local structure that is approximately 3 nm in diameter and over several hundred nanometers in length. Oscillatory rheology suggests that the peptidic network viscoelastic behavior follows that theoretically predicted for heavily cross-linked, semiflexible polymer networks.