A Review of Myocardial Normothermia: Its Theoretical Basis and the Potential Clinical Benefits in Cardiac Surgery
A Review of Myocardial Normothermia: Its Theoretical Basis and the Potential Clinical Benefits in Cardiac Surgery
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心肌常温的回顾：其理论基础和在心脏手术中的潜在临床益处
DOI：
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发表时间：
2000
期刊：
影响因子：
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通讯作者：
F. Trivin
中科院分区：
文献类型：
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作者：
D. Gaillard;O. Bical;D. Paumier;F. Trivin
心脏手术中的心肌保护旨在保护心肌功能，同时提供无血和静止的手术野，使手术更容易。心肌保护是通过使用低温降低对氧气的需求和使用钾输注产生机电心脏骤停来实现的，钾输注允许在无跳动的心脏上进行手术。低温的有害影响包括酶系统的功能障碍。酸中毒的发展。组织供氧减少血液粘度增加和红细胞变形性降低。90%的耗氧量减少是通过诱导机电停止获得的，诱导低温几乎没有额外的好处。维持全身和心肌正常体温可减少问题，并为心肺转流（CPS）提供更符合生理的方法。目前使用常温保护获得的结果非常令人鼓舞。这是一个更容易的便宜的选择。本文综述了目前对常温的益处的认识。基于实验和临床研究。© 2000国际心血管外科学会，Elsevier Science Ltd出版。保留所有权利
Myocardial protection during cardiac surgery aims to preserve myocardial function while providing a bloodless and motionless operating field to make surgery easier. Myocardial protection is achieved by decreasing the oxygen needsusing hypothermia and producing electromechanical cardiac arrest using potassium infusion which allows surgery to be performed on a nonbeating heart. The deleterious effects of hypothermia include dysfunction of enzymatic systems. development of acidosis. a decrease in tissue oxygen delivery. an increase in blood viscosity and a decrease in erythrocyte deformability. Ninety percent of the decrease in oxygen consumption is obtained by inducing electromechanical arrest and inducing hypothermia has little additional benefit. Maintenanceof systemic and myocardialnormothermia reduces problems and provides a more physiological approach for cardiopulmonary bypass (CPS). The current results obtained using normothermic protection are very encouraging. and it is an easier inexpensive option. This review summarizes the current knOWledge on the benefits of normothermia. based upon experimental and clinical studies. © 2000 The International Society for Cardiovascular Surgery, Published by Elsevier Science Ltd. All rights reserved
用冷停跳液快速冷却挛缩。
DOI：
10.1016/s0003-4975(97)00087-8
发表时间：
1997
期刊：
The Annals of thoracic surgery
影响因子：
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作者：
Lahorra,JA;Torchiana,DF;TolisJr,G;Bashour,CA;Hahn,C;Titus,JS;Geffin,GA;Daggett,WM
通讯作者：
Daggett,WM