Alcohol and associated characteristics among older persons living with human immunodeficiency virus on antiretroviral therapy.
Alcohol and associated characteristics among older persons living with human immunodeficiency virus on antiretroviral therapy.
复制标题
接受抗逆转录病毒治疗的人类免疫缺陷病毒感染老年人的酒精和相关特征。
DOI：
10.1080/08897077.2014.890997
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发表时间：
2014
期刊：
影响因子：
3.5
通讯作者：
Catz,SherylL
中科院分区：
文献类型：
--
作者：
Williams,EmilyC;Bradley,KatharineA;Balderson,BenjaminH;McClure,JenniferB;Grothaus,Lou;McCoy,Katryna;Rittmueller,StaceyE;Catz,SherylL
背景饮酒，特别是不健康的饮酒，与艾滋病病毒感染者（PLWH）的不良人类免疫缺陷病毒（HIV）相关结果有关。尽管≥ 50岁的PLWH比例快速增长，但在该人群中，酒精使用及其相关特征未得到充分描述。作者描述了酒精的使用，严重程度，和相关的特征，使用的数据来自一个样本的PLWH ≥ 50岁谁参加了一个试验的电话为基础的干预，以提高坚持抗逆转录病毒疗法（ART）MethodsParticipants被招募从获得性免疫缺陷综合征（AIDS）服务组织在9个州，包括PLWH ≥ 50岁谁是规定的ART，在筛选时报告了次优的依从性（在筛选前30天内缺失> 1.5天的药物治疗或在> 3天提前或延迟2小时服用药物），并同意参与。在基线时评估AUDIT-C（酒精使用障碍识别测试-消费）酒精筛查、社会人口学特征、物质使用和精神健康共病。AUDIT-C评分分为不饮酒、低水平饮酒、轻度-中度不健康饮酒和重度不健康饮酒（分别为0、1 - 3、4 - 6和7 - 12）。分析描述和比较饮酒状态（任何/无）和AUDIT-C类别之间drinkers.ResultsAmong 447名参与者，57%的饮酒报告在过去的一年（35%，15%和7%报告低水平饮酒，轻度中度不健康饮酒，严重不健康饮酒，分别）的特点。任何饮酒在男性和那些女同性恋、男同性恋、双性恋或变性人（LGBT）、已婚/有伴侣、接受过去年的酒精治疗、从未使用过注射毒品的人中最常见（P值均<.05）。种族，就业状况，过去一年的酒精治疗和积极的抑郁症筛查的差异（P值均<.05）在AUDIT-C类别中观察到，非裔美国人种族，不到全职工作，过去一年的酒精治疗和积极的抑郁症筛查在那些最严重的不健康饮酒者中最常见。大多数人报告去年使用酒精，22%的人对不健康的酒精使用呈阳性。任何和不健康的酒精使用与人口统计学，抑郁症和物质使用史有关。需要进一步研究老年艾滋病毒携带者饮酒问题。
BackgroundAlcohol use, and particularly unhealthy alcohol use, is associated with poor human immunodeficiency virus (HIV)-related outcomes among persons living with HIV (PLWH). Despite a rapidly growing proportion of PLWH ≥50 years, alcohol use and its associated characteristics are underdescribed in this population. The authors describe alcohol use, severity, and associated characteristics using data from a sample of PLWH ≥50 years who participated in a trial of a telephone-based intervention to improve adherence to antiretroviral therapy (ART).MethodsParticipants were recruited from acquired immunodeficiency syndrome (AIDS) service organizations in 9 states and included PLWH ≥50 years who were prescribed ART, reported suboptimal adherence at screening (missing >1.5 days of medication or taking medications 2 hours early or late on >3 days in the 30 days prior to screening), and consented to participate. The AUDIT-C (Alcohol Use Disorders Identification Test—Consumption) alcohol screen, sociodemographic characteristics, substance use, and mental health comorbidity were assessed at baseline. AUDIT-C scores were categorized into nondrinking, low-level drinking, and mild-moderate unhealthy, and severe unhealthy drinking (0, 1–3, 4–6, and 7–12, respectively). Analyses described and compared characteristics across drinking status (any/none) and across AUDIT-C categories among drinkers.ResultsAmong 447 participants, 57% reported drinking in the past year (35%, 15%, and 7% reported low-level drinking, mild-moderate unhealthy drinking, and severe unhealthy drinking, respectively). Any drinking was most common among men and those who were lesbian, gay, bisexual, or transgender (LGBT), married/partnered, had received past-year alcohol treatment, and never used injection drugs (Pvalues all <.05). Differences in race, employment status, past-year alcohol treatment, and positive depression screening (Pvalues all <.05) were observed across AUDIT-C categories, with African American race, less than full-time employment, past-year alcohol treatment, and positive depression screening being most common among those with the most severe unhealthy drinking.ConclusionsIn this sample of older PLWH with suboptimal ART adherence, a majority reported past-year alcohol use and 22% screened positive for unhealthy alcohol use. Any and unhealthy alcohol use were associated with demographics, depression, and substance use history. Further research is needed regarding alcohol use among older PLWH.