Different command neurons select different outputs from a shared premotor interneuron of crayfish tail-flip circuitry.
Different command neurons select different outputs from a shared premotor interneuron of crayfish tail-flip circuitry.
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不同的命令神经元从小龙虾甩尾电路的共享前运动中间神经元中选择不同的输出。
DOI：
10.1126/science.7292013
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发表时间：
1981
期刊：
影响因子：
--
通讯作者：
Bellman,KL
中科院分区：
文献类型：
--
作者：
Kramer,AP;Krasne,FB;Bellman,KL
在小龙虾的双边对interneurons（I3的）参与产生两种类型的甩尾逃避反应，一个介导的巨型神经元和其他nongiant电路。I3与运动神经元和其他参与甩尾的中间神经元建立各种输出连接。运动神经元的输出包括尾屈肌运动神经元上的强突触，其在由外侧巨纤维介导的甩尾过程中的活动将是适应不良的。侧巨人总是驱动I3的，但也驱动抑制神经元，以防止I3的不期望的输出，同时允许它们的自适应输出被表达。它通常是适应性的尾巴翻转发起的非巨人电路利用尾屈肌肌肉，I3强烈兴奋。在这种甩尾过程中，I3经常被激发，这种激发对于驱动尾屈肌很重要。
In the crayfish a bilateral pair of interneurons (the I3's) are involved in the generation of two types of tail-flip escape responses, one mediated by giant neurons and the other by nongiant circuitry. The I3's make a variety of output connections with the motoneurons and with other interneurons involved in tail flipping. The motoneuronal outputs include strong synapses on telson flexor motoneurons, whose activity during tail flips mediated by lateral giant fibers would be maladaptive. The lateral giants always drive the I3's, but also drive inhibitory neurons that prevent the undesirable outputs of the I3's while permitting their adaptive outputs to be expressed. It is often adaptive for tail flips initiated by nongiant circuitry to utilize the telson flexor muscles that I3 strongly excites. During such tail flips I3 is often fired, and this firing is important in driving the telson flexors.