Intracardiac Vortex Dynamics by High-Frame-Rate Doppler Vortography-In Vivo Comparison With Vector Flow Mapping and 4-D Flow MRI
Intracardiac Vortex Dynamics by High-Frame-Rate Doppler Vortography-In Vivo Comparison With Vector Flow Mapping and 4-D Flow MRI
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DOI：
10.1109/tuffc.2016.2632707
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发表时间：
2017-02-01
影响因子：
3.6
通讯作者：
Garcia, Damien
中科院分区：
文献类型：
--
作者：
Faurie, Julia;Baudet, Mathilde;Garcia, Damien
近年来的研究表明，心内涡流显像对舒张功能的早期诊断具有重要的临床意义。多普勒涡流描记术已被引入作为一种简单的彩色多普勒方法来检测和量化室内涡流。该方法能够根据多普勒速度场中反对称模式的识别来定位涡核。由于心脏是一个快速运动的器官，因此需要高帧速率来破译心脏活动期间的全血涡旋动力学。在本文中，我们采用了涡流法，以高帧频超声心动图使用圆形波。时间分辨多普勒涡图首先在体外一个理想的强制涡流验证。我们观察到的核心涡度确定的高帧频涡度和地面真实涡度之间有很强的相关性。还在10名健康志愿者体内使用高帧率双功超声检查进行了涡流图测试。在两三个连续的心动周期期间跟踪在左心室充盈期间形成的主涡旋，并且以高达80个双工图像/心跳的采样率确定其核心涡旋。评价了三个超声心动图心尖视图。涡图导出的涡度进行了比较与返回的2-D矢量流映射方法。在10名志愿者中的4名中也进行了与4-D流动磁共振成像的比较。在确定早期填充期间的峰值涡度时，观察到强方法间协议。结论：高帧频多普勒血流图能准确地研究舒张期血流动力学。
Recent studies have suggested that intracardiac vortex flow imaging could be of clinical interest to early diagnose the diastolic heart function. Doppler vortography has been introduced as a simple color Doppler method to detect and quantify intraventricular vortices. This method is able to locate a vortex core based on the recognition of an antisymmetric pattern in the Doppler velocity field. Because the heart is a fast-moving organ, high frame rates are needed to decipher the whole blood vortex dynamics during diastole. In this paper, we adapted the vortography method to high-frame-rate echocardiography using circular waves. Time-resolved Doppler vortography was first validated in vitro in an ideal forced vortex. We observed a strong correlation between the core vorticity determined by high-frame-rate vortography and the ground-truth vorticity. Vortography was also tested in vivo in ten healthy volunteers using high-frame-rate duplex ultrasonography. The main vortex that forms during left ventricular filling was tracked during two-three successive cardiac cycles, and its core vorticity was determined at a sampling rate up to 80 duplex images per heartbeat. Three echocardiographic apical views were evaluated. Vortography-derived vorticities were compared with those returned by the 2-D vector flow mapping approach. Comparison with 4-D flow magnetic resonance imaging was also performed in four of the ten volunteers. Strong intermethod agreements were observed when determining the peak vorticity during early filling. It is concluded that high-frame-rate Doppler vortography can accurately investigate the diastolic vortex dynamics.