The ID23-1 structural biology beamline at the ESRF
The ID23-1 structural biology beamline at the ESRF
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DOI：
10.1107/s0909049506004341
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发表时间：
2006-05-01
影响因子：
2.5
通讯作者：
Mitchell, E
中科院分区：
文献类型：
--
作者：
Nurizzo, D;Mairs, T;Mitchell, E
对获得大分子晶体学同步加速器光束时间的需求持续增加。为了满足这一需求，ESRF已经构建了一个双站束线使用倾斜的波荡器系统作为X射线源。要构建的光束线的第一阶段是ID 23 -1，这是一个具有微焦点X射线束的可调MAD能力的站。该光束线使用了特征良好的光学元件：一个通道切割单色仪，带有一个高精度的环形反射镜，用于聚焦X射线束。光束线的设计目的是提供高水平的自动化，为蛋白质晶体学创造一个类似工业的环境。一个新的软件套件已经开发，允许可靠的光束线用户和光束线工作人员容易操作。内置高级别诊断功能，可快速排除故障。这些发展现在正在出口到ESRF大分子晶体学光束线复杂，并已在一个模块化的方式，以促进运输到其他同步加速器。
The demand for access to macromolecular crystallography synchrotron beam time continues to increase. To meet this demand the ESRF has constructed a dual station beamline using a canted undulator system as the X-ray source. The first phase of the beamline to be constructed is ID23-1, a tunable MAD-capable station with a mini-focus X-ray beam. The beamline makes use of well characterized optical elements: a channel-cut monochromator with a high-precision toroidal mirror to focus the X-ray beam. The beamline has been conceived with the aim of providing high levels of automation to create an industrial-like environment for protein crystallography. A new software suite has been developed to permit reliable easy operation for the beamline users and beamline staff. High levels of diagnostics are built in to allow rapid troubleshooting. These developments are now being exported to the ESRF macromolecular crystallography beamline complex and have been made in a modular fashion to facilitate transportability to other synchrotrons.