Increased prevalence of tension-type headache over a 12-year period is related to increased pain sensitivity. A population study
Increased prevalence of tension-type headache over a 12-year period is related to increased pain sensitivity. A population study
复制标题
DOI：
10.1111/j.1468-2982.2006.01248.x
复制
发表时间：
2007-02-01
期刊：
影响因子：
4.9
通讯作者：
Jensen, R.
中科院分区：
文献类型：
--
作者：
Buchgreitz, L.;Lyngberg, A. C.;Jensen, R.
我们最近报道了在丹麦年轻人群中12年来紧张型头痛（TTH）的患病率和频率增加。本研究的目的是分析这种增加是否与疼痛敏感性增加有关。该研究是一项大型丹麦人群研究的横断面重复。它比较了2001年的113名25-36岁的受试者和1989年的221名可比受试者。2001年的租金比1989年高得多。当根据头痛的存在进行分层时，压痛的增加仅在频繁TTH的女性中具有临床和统计学意义。与1989年相比，2001年频繁TTH女性的压痛阈值明显降低。人群触痛的增加可能预示着将来TTH的患病率会更高。这些变化支持TTH的中枢敏感化假说。
We recently reported an increase in prevalence and frequency of tension-type headache (TTH) over a 12-year period in the young Danish population. The aim of the present study was to analyse whether this increase was related to increased pain sensitivity. The study was a cross-sectional replicate of a large Danish population study. It compared 113 subjects aged 25-36 years in 2001, with 221 comparable subjects in 1989. Tenderness was considerably higher in 2001 than in 1989. When stratified according to presence of headache, the increase in tenderness was clinically and statistically significant only in women with frequent TTH. The pressure pain threshold was significantly lower in 2001 compared with 1989 in women with frequent TTH. The increase in tenderness in the population may predict an even higher prevalence of TTH in future. The changes support the hypothesis of central sensitization in TTH.