Cellular rejuvenation to combat HIV-1-related neurocognitive impairment.

Cellular rejuvenation to combat HIV-1-related neurocognitive impairment.
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细胞再生对抗 HIV-1 相关的神经认知障碍。

DOI:
10.1016/j.tim.2023.09.011
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发表时间:
2024
影响因子:
15.9
通讯作者:
Evering,TeresaH
Evering,TeresaH
中科院分区:
生物学1区
文献类型:
--
作者:
Ostermann,PhilippN;Evering,TeresaH

文献摘要

相似文献

HIV-1相关的神经认知障碍影响了相当大比例的HIV感染者,其发病机制与大脑加速老化有关。该论坛探讨了细胞年轻化策略的应用,以靶向大脑衰老的分子机制,促进神经元健康,并对抗认知能力下降。
HIV-1-related neurocognitive impairment affects a significant proportion of people living with HIV, and accelerated brain aging has been implicated in its pathogenesis. This forum explores the application of cellular rejuvenation strategies to target molecular mechanisms of brain aging, promote neuronal health, and combat cognitive decline.