Iron in fetal and neonatal nutrition
Iron in fetal and neonatal nutrition
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DOI：
10.1016/j.siny.2006.10.007
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发表时间：
2007-02-01
影响因子：
3
通讯作者：
Georgieff, Michael K.
中科院分区：
文献类型：
--
作者：
Rao, Raghavendra;Georgieff, Michael K.
在胎儿和新生儿时期，铁缺乏和铁过量都预示着器官系统发育不良。缺铁、糖尿病、高血压、吸烟和早产等产妇状况是围产期缺铁的常见原因。围产期缺铁婴儿普遍存在长期的神经发育、损伤和未来缺铁的易感性，这需要对有缺铁风险的婴儿进行早期诊断、最佳治疗和充分的随访。然而，由于潜在的氧化介导的组织损伤，铁超载应避免在围产期，特别是早产儿。(c) 2006 Elsevier Ltd.版权所有。
Both iron deficiency and iron excess during the fetal and neonatal period bode poorly for developing organ systems. Maternal conditions such as iron deficiency, diabetes mellitus, hypertension and smoking, and preterm birth are the common causes of perinatal iron deficiency. Long-term neurodevetopmental, impairments and predisposition to future iron deficiency that are prevalent in infants with perinatal iron deficiency require early diagnosis, optimal treatment and adequate follow-up of infants at risk for the condition. However, due to the potential for oxidant-mediated tissue injury, iron overload should be avoided in the perinatal period, especially in preterm infants. (c) 2006 Elsevier Ltd. All rights reserved.