Trends in risk factors for cardiovascular disease among children and adolescents in the United States
Trends in risk factors for cardiovascular disease among children and adolescents in the United States
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DOI：
10.1542/peds.2004-0674
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发表时间：
2004-12-01
期刊：
影响因子：
8
通讯作者：
Ajani, UA
中科院分区：
文献类型：
--
作者：
Ford, ES;Mokdad, AH;Ajani, UA
背景近几十年来儿童和青少年肥胖患病率的增加可能影响了肥胖相关的心血管疾病危险因素的趋势。我们使用的数据为12 665名儿童和青少年，2至17岁，从第三次全国健康和营养调查（1988-1994年）和3611名儿童和青少年从全国健康和营养调查1999- 2000年。对于2至17岁的参与者，男性受试者的腰围增加了1.6 cm，女性受试者增加了2.4 cm。8至17岁的儿童和青少年的平均收缩压增加了2.2毫米汞柱。在12至17岁的儿童和青少年中，甘油三酯（8.8 mg/dL）和葡萄糖（2.5 mg/dL）浓度显著降低。总胆固醇、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇和糖化血红蛋白的平均浓度相对不变。一些危险因素的变化因年龄而异。1990年代儿童和青少年中危险因素的时间趋势呈现出不同的模式。肥胖患病率日益增加对儿童和青少年心血管健康的影响仍不清楚。
Background. The increasing prevalence of obesity among children and adolescents in recent decades might have affected trends in obesity-associated risk factors for cardiovascular disease.Participants and Methods. We used data for 12 665 children and adolescents, 2 to 17 years of age, from the Third National Health and Nutrition Examination Survey (1988-1994) and for 3611 children and adolescents from National Health and Nutrition Examination Survey 1999-2000.Results. For participants 2 to 17 years of age, waist circumference increased 1.6 cm among male subjects and 2.4 cm among female subjects. Mean systolic blood pressure increased by 2.2 mm Hg among children and adolescents 8 to 17 years of age. There were significant decreases in concentrations of triglycerides (8.8 mg/dL) and glucose (2.5 mg/dL) among children and adolescents 12 to 17 years of age. Mean concentrations of total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, and glycosylated hemoglobin were relatively unchanged. Some changes in means of risk factors varied according to age.Conclusions. The temporal trends for risk factors among children and adolescents during the 1990s exhibited different patterns. The effects of the increasing prevalence of obesity on the cardiovascular health of children and adolescents remain unclear.