Cytology Reporting System for Lung Cancer from the Japan Lung Cancer Society and the Japanese Society of Clinical Cytology: An Extensive Study Containing More Benign Lesions
Cytology Reporting System for Lung Cancer from the Japan Lung Cancer Society and the Japanese Society of Clinical Cytology: An Extensive Study Containing More Benign Lesions
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日本肺癌学会和日本临床细胞学会的肺癌细胞学报告系统：包含更多良性病变的广泛研究
DOI：
10.1159/000520426
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发表时间：
2021
期刊：
影响因子：
1.8
通讯作者：
Nakatsuka
中科院分区：
文献类型：
--
作者：
Yoshizawa Akihiko;Hiroshima Kenzo;Takenaka Akemi;Haba Reiji;Kawahara Kunimitsu;Minami Yuko;Kakinuma Hirokuni;Shibuki Yasuo;Miyake Shinji;Kajio Kenta;Kiyonaga Kana;Nagatomo Moe;Nishimura Sanako;Mano Masayuki;Matsubayashi Jun;Motoi Noriko;Nagao T.;Nakatsuka
日本肺癌学会（JLCS）和日本临床细胞学学会（JSCC）提出了一个新的肺癌细胞学四级报告系统（JLCS-JSCC系统）。在此提案之前，Papanicolaou细胞病理学会（PSC）已经提出了一个修订后的报告体系（PSC体系），除了JLCS-JSCC体系的4个类别外，还包括“肿瘤、良性肿瘤和低级别癌”类别（NB-LG类别）。本研究旨在通过与PSC系统相比具有更多良性病变的额外数据集来评估JLCS-JSCC系统的观察者间一致性。方法对167例呼吸系统细胞学样本进行分析，其中17例为良性病变。根据JLCS-JSCC系统和PSC系统，7名观察员通过审查每个病例的papanicolao染色玻片，将这些病例分为每个类别。结果JLCS-JSCC系统和PSC系统的观察者间一致性为中等（k= 0.499）。167例样本中，17例为良性病变：7例肺错构瘤，5例硬化性肺细胞瘤，2例鳞状乳头状瘤，1例孤立性纤维瘤，1例脑膜瘤，1例淋巴细胞增生。不同的样本类型如下：11个触摸涂片，3个刷涂片，2个愿望，1个痰样。在JLCS-JSCC系统中，超过一半的观察者将14个样本（82.3%）归类为“阴性”或“非典型”。相反，在JLCS-JSCC系统中，有3个样本被超过一半的观察者归类为“可疑”或“恶性”。另一方面，有11个样本（64.7%）被超过一半的PSC系统观察者归类为NB-LG类别。结论JLCS-JSCC系统的符合率略高于PSC系统；然而，在JLCS-JSCC和PSC系统中，观察员间的一致意见是中等的。这些结果表明JLCS-JSCC和PSC系统在临床上都是有用的。因此，这两种系统都有望有临床应用。因此，将这两种系统整合起来，构建一个通用的系统，在临床实践中得到更广泛的应用是很重要的。
IntroductionThe Japan Lung Cancer Society (JLCS) and the Japanese Society of Clinical Cytology (JSCC) have proposed a new four-tiered cytology reporting system for lung carcinoma (JLCS-JSCC system). Prior to the proposal, the Papanicolaou Society of Cytopathology (PSC) had proposed a revised reporting system (PSC system), which comprises the “neoplastic, benign neoplasm, and low-grade carcinoma” category (NB-LG category), in addition to the 4 categories of the JLCS-JSCC system. This study aimed to evaluate the interobserver agreement of the JLCS-JSCC system with an additional dataset with more benign lesions in comparison with the PSC system.MethodsWe analyzed 167 cytological samples, which included 17 benign lesions, obtained from the respiratory system. Seven observers classified these cases into each category by reviewing one Papanicolaou-stained slide per case according to the JLCS-JSCC system and PSC system.ResultsThe interobserver agreement was moderate in the JLCS-JSCC (k= 0.499) and PSC (k= 0.485) systems. Of the 167 samples, 17 samples were benign lesions: 7 pulmonary hamartomas, 5 sclerosing pneumocytomas, 2 squamous papillomas, one solitary fibrous tumor, one meningioma, and one lymphocytic proliferation. There were diverse sample types as follows: 11 touch smears, 3 brushing smears, 2 aspirations, and one sputum sample. Fourteen samples (82.3%) were categorized into “negative” or “atypical” by more than half of the observers in the JLCS-JSCC system. Conversely, 3 samples were categorized as “suspicious” or “malignant” by more than half of the observers in the JLCS-JSCC system. On the other hand, 11 samples (64.7%) were categorized into the NB-LG category by more than half of the observers in the PSC system.ConclusionsThe concordance rate in the JLCS-JSCC system was slightly higher than that in the PSC system; however, the interobserver agreement was moderate in both the JLCS-JSCC and PSC systems. These results indicate that both the JLCS-JSCC and PSC systems are clinically useful. Therefore, both systems are expected to have clinical applications. It may be important to integrate the 2 systems and construct a universal system that can be used more widely in clinical practice.
DOI：
10.1038/s41379-020-00698-2
发表时间：
2021-04
期刊：
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
影响因子：
--
作者：
Ginter PS;Idress R;D'Alfonso TM;Fineberg S;Jaffer S;Sattar AK;Chagpar A;Wilson P;Harigopal M
通讯作者：
Harigopal M
巴氏细胞病理学学会关于从呼吸道获得的细胞学标本检查的指南。
影响因子：
7.5
作者：
S. Allan;C. B. Lawrence;N. J. Rothwell
通讯作者：
N. J. Rothwell
影响因子：
1.3
作者：
Canberk, Sule;Montezuma, Diana;Schmitt, Fernando
通讯作者：
Schmitt, Fernando