Ameloblastic carcinoma: Report of an aggressive case with multiple bony metastases

Ameloblastic carcinoma: Report of an aggressive case with multiple bony metastases
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DOI:
10.1053/ajot.2003.15
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发表时间:
2003-01-01
影响因子:
2.5
通讯作者:
Hicks, WL
Hicks, WL
中科院分区:
医学3区
文献类型:
--
作者:
Datta, R;Winston, JS;Hicks, WL

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造釉细胞癌是一种罕见的原发于颌面骨骼的肿瘤,好发于下颚骨。这些病变最初可能表现出成釉细胞瘤的组织学特征,随着时间的推移去分化。其他成釉细胞癌最初表现为成釉细胞瘤的形态学特征,伴有上皮去分化区。我们在此报告一位22岁的白色男性罹患侵袭性成釉细胞癌的罕见病例,他在初次诊断后4年发生广泛的骨转移并死亡。
Ameloblastic carcinoma is a rare primary tumor of the maxillofacial skeleton with a distinct predilection for the mandible. These lesions may initially show histologic features of ameloblastoma that dedifferentiate over time. Other ameloblastic carcinomas initially present with morphologic features suggestive of ameloblastoma with areas of epithelial dedifferentiation. We herein report a rare case of aggressive ameloblastic carcinoma in a 22-year-old white man who developed widespread bony metastases and expired 4 years after initial diagnosis.