The Clinical Global Impression-Schizophrenia scale:: a simple instrument to measure the diversity of symptoms present in schizophrenia
The Clinical Global Impression-Schizophrenia scale:: a simple instrument to measure the diversity of symptoms present in schizophrenia
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DOI：
10.1034/j.1600-0447.107.s416.5.x
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发表时间：
2003-05-01
影响因子：
6.7
通讯作者：
Jones, PB
中科院分区：
文献类型：
--
作者：
Haro, JM;Kamath, SA;Jones, PB
目的：描述临床总体印象-精神分裂症（CGI-SCH）量表的开发和验证，该量表旨在评估精神分裂症的阳性、阴性、抑郁和认知症状。方法：CGI- sch量表改编自CGI量表。通过与阳性和阴性症状严重程度（PANSS）和整体功能评估（GAF）量表进行比较，评估并发效度和对变化的敏感性。为了评估评分者之间的信度，所有患者都由两位临床医生进行评估。结果：对114例患者进行了症状评估。CGI-SCH与GAF和PANSS评分之间的相关系数很高（大多数高于0.75），阳性和阴性症状的相关系数最高。除了一个维度（抑郁维度，ICC=0.64）外，其他维度的信度都很高（类内相关系数，ICC>0.70）。结论：CGI-SCH量表是一种有效、可靠的评估精神分裂症严重程度和治疗反应的工具。鉴于其简单、简洁和临床效度，该量表适用于观察性研究和常规临床实践。
Objective: To describe the development and validation of the Clinical Global Impression-Schizophrenia (CGI-SCH) scale, designed to assess positive, negative, depressive and cognitive symptoms in schizophrenia.Method: The CGI-SCH scale was adapted from the CGI scale. Concurrent validity and sensitivity to change were assessed by comparison with the Positive and Negative Symptom Severity (PANSS) and Global Assessment of Functioning (GAF) scales. To evaluate inter-rater reliability, all patients were assessed by two clinicians.Results: Symptoms were assessed in 114 patients. Correlation coefficients between the CGI-SCH and the GAF and PANSS scores were high (most above 0.75), and were highest for positive and negative symptoms. Reliability was substantial (intraclass correlation coefficient, ICC>0.70) in all but one dimension (depressive dimension, ICC=0.64).Conclusion: The CGI-SCH scale is a valid, reliable instrument to evaluate severity and treatment response in schizophrenia. Given its simplicity, brevity and clinical face validity, the scale is appropriate for use in observational studies and routine clinical practice.