Enamel remineralization effect of a dentifrice containing calcium sodium phosphosilicate: an optical coherence tomography observation
Enamel remineralization effect of a dentifrice containing calcium sodium phosphosilicate: an optical coherence tomography observation
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DOI：
10.1080/00016357.2016.1277588
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发表时间：
2017-01
影响因子：
2
通讯作者：
Saki Matsuyoshi;Ryosuke Murayama;Shunsuke Akiba;Chiaki Yabuki;T. Takamizawa;H. Kurokawa;M. Miyazaki
中科院分区：
文献类型：
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作者：
Saki Matsuyoshi;Ryosuke Murayama;Shunsuke Akiba;Chiaki Yabuki;T. Takamizawa;H. Kurokawa;M. Miyazaki
摘要目的：本研究的目的是使用光学相干断层扫描（OCT）检查含有5%磷硅酸钙钠（CSP）的糊剂对釉质矿化的影响。材料与方法：将牛切牙切成矩形。一组5个标本用不饱和的0.1M乳酸缓冲液（pH4.75）处理10 min，然后置于人工唾液（pH7.0）中（De组）。其他标本在含有CSP的牙膏溶液中保存10 min，然后在人工唾液中保存前每天两次在乳酸缓冲液中浸泡10 min（CSP组）。另一组仅储存在人工唾液中（对照组）。在釉质表面的选定位置上进行OCT成像。在样品上的六个区域中的每一个中记录1/e2处的峰强度和宽度并取平均值，每组的样品量为六个。以峰强度面积计算积分值，单位为dB × μm。对每组数据进行单因素重复测量ANOVA和Tukey HSD检验（α = 0.05）。结果：各组积分值变化不同。在对照组中观察到积分值轻微但显著增加，而在De组中观察到积分值轻微但显著降低。CSP组的积分值增加。结论：再矿化发生后，浸泡在牙膏含有CSP。
Abstract Objective: The purpose of this study was to examine the effects of a dentifrice containing 5% calcium sodium phosphosilicate (CSP) on the remineralization of the enamel using optical coherence tomography (OCT). Materials and methods: Bovine incisors were sliced and shaped in a rectangular form. One group of five specimens was treated with undersaturated 0.1 M lactic acid buffer solution (pH 4.75) for 10 min and then placed in artificial saliva (pH 7.0) (De group). Other specimens were stored in solutions of toothpaste containing CSP for 10 min, followed by 10-min immersion in the lactic acid buffer solution twice a day before storage in artificial saliva (CSP group). An additional group was stored in only artificial saliva (control group). OCT imaging on the selected location of the enamel surface was performed. The peak intensity and width at 1/e2 were recorded in each of the six areas on the sample and averaged, and the sample size of each group was six. The integrated value in units (dB × μm) was calculated in the area of peak intensity. The data for each group was subjected to one-way repeated-measures ANOVA and Tukey HSD tests (α = 0.05). Results: The changes in integrated values of each group were different. A slight but significant increase in the integrated value was observed in the control group, whereas a slight but significant decrease in the value was observed the De group. Integrated values increased in the CSP group. Conclusions: Remineralization occurred upon immersion in the toothpaste containing CSP.