The response of Crohn's strictures to endoscopic balloon dilation
The response of Crohn's strictures to endoscopic balloon dilation
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DOI：
10.1111/j.1365-2036.2009.04225.x
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发表时间：
2010-03-15
影响因子：
7.6
通讯作者：
Pfeiffer, A.
中科院分区：
文献类型：
--
作者：
Mueller, T.;Rieder, B.;Pfeiffer, A.
BackgroundEndoscopic球囊扩张已被证明是一种替代手术治疗克罗恩病的症状性狭窄。AimTo分析狭窄的类型，从头或血管狭窄，他们的位置和他们的长度对内镜球囊扩张的结果的影响。MethodsBetween 1999年12月和2008年6月，55例患者进行了93球囊扩张74症状性狭窄。一个狭窄位于十二指肠，39狭窄在末端回肠，17在回盲部吻合后，前切除和17在colon.ResultsEndoscopic治疗成功的76%的患者在观察期为44（1-103）个月。在这些患者中，24%需要手术。所有接受手术的患者均在回肠末端新发狭窄。这些狭窄明显长于回肠狭窄，回应内镜治疗[7.5（1-25）cm与2.5（1 - 25）cm; P = 0.006]。结论内镜球囊扩张术的长期成功取决于狭窄的类型，它们的位置和长度。仅在回肠末端长段狭窄中观察到内镜治疗失败。
BackgroundEndoscopic balloon dilation has been shown to be an alternative to surgery in the treatment of Crohn's symptomatic strictures.AimTo analyse the impact of the type of the strictures-de novo or anastomotic-their location and their length on the outcome of endoscopic balloon dilation.MethodsBetween December 1999 and June 2008, 55 patients underwent 93 balloon dilations for 74 symptomatic strictures. One stricture was located in the duodenum, 39 strictures were in the terminal ileum, 17 at the ileocoecal anastomosis after a preceding resection and 17 in the colon.ResultsEndoscopic treatment was successful in 76% of the patients during an observation period of 44 (1-103) months. Of the patients, 24% required surgery. All patients who underwent surgery had de novo strictures in the terminal ileum. These strictures were significantly longer compared with the ileal strictures that responded to endoscopic treatment [7.5 (1-25) cm vs. 2.5 (1-25) cm; P = 0.006].ConclusionsThe long-term success of endoscopic balloon dilation depends on the type of the strictures, their location and their length. Failure of endoscopic treatment was observed only in long-segment strictures in the terminal ileum.