Cry features reflect pain intensity in term newborns: An alarm threshold
Cry features reflect pain intensity in term newborns: An alarm threshold
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DOI：
10.1203/01.pdr.0000099793.99608.cb
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发表时间：
2004-01-01
影响因子：
3.6
通讯作者：
Buonocore, G
中科院分区：
文献类型：
--
作者：
Bellieni, CV;Sisto, R;Buonocore, G
本研究的目的是评估足月新生儿在不同疼痛水平下的哭声声谱差异。57个连续出生的新生儿进行了评估，在足跟穿刺不同的镇痛技术。记录哭泣并分析频谱图。在采样后，对每个婴儿进行DAN（DoubletAigue do Nouveau-ne）量表的疼痛评分。考虑三个特征并将其与相应的DAN分数相关联：1）整个频谱形式; 2）发出的第一声啼哭的基频（F-0）;以及3）归一化至其最大值的均方根声压。在发出第一声啼哭后，DAN评分>8的婴儿，但DAN评分小于或等于8的婴儿（p < 0.001），表现出一种模式（“警笛般的哭声”），其特征是一系列几乎相同的哭声，周期为1秒左右。均方根（r（2）= 89%，p < 0.01）、F-0（r（2）= 32%，p < 0.05）、警笛声（r（2）= 68.2%，p = 0.02）和DAN评分之间存在统计学显著相关性。在DAN评分小于或等于8的新生儿中，F-0与DAN评分无显著相关性（r（2）= 1.4%，p = 0.94），DAN评分>8的婴儿的F-0显著高于DAN评分较低的婴儿（p = 0.016）。警报阈值存在于高（>8）和低（小于或等于8）DAN分数之间：哭泣在这两组中具有不同的特征。当疼痛超过DAN评分8时，通常会发出高音的第一声喊叫，然后是警笛声，声音水平保持在接近最大值。
The purpose of this study was to assess differences in sound spectra of crying of term newborns in relation to different pain levels. Fifty-seven consecutively born neonates were evaluated during heel-prick performed with different analgesic techniques. Crying was recorded and frequency spectrograms analyzed. A pain score on the DAN (Douleur Aigue do Nouveau-ne) scale was assigned to each baby after the sampling. Three features were considered and correlated with the corresponding DAN scores: 1) whole spectral form; 2) the fundamental frequency of the first cry emitted (F-0); and 3) root mean square sound pressure normalized to its maximum. After emission of the first cry, babies with DAN scores >8, but not with DAN scores less than or equal to8 (p < 0.001), showed a pattern ("siren cry") characterized by a sequence of almost identical cries with a period on the order of 1 s. A statistically significant correlation was found between root mean square (r(2) = 89%, p < 0.01), F-0 (r(2) = 32%, p < 0.05), siren cry (r(2) = 68.2%, p = 0.02), and DAN score. F-0 did not show significant correlation with DAN score in the subset of neonates with DAN scores less than or equal to8 (r(2) = 1.4%, p = 0.94), and babies with a DAN score >8 had a significantly higher F-0 than those with lower DAN scores (p = 0.016). An alarm threshold exists between high (>8) and low (less than or equal to 8) DAN scores: crying has different features in these two groups. When pain exceeds a DAN score of 8, usually a first cry at a high pitch is emitted, followed by the siren cry, with a sound level maintained near its maximum.