Recognition and Reporting of AKI in Very Low Birth Weight Infants

Recognition and Reporting of AKI in Very Low Birth Weight Infants
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DOI:
10.2215/cjn.05190514
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发表时间:
2014-12-01
影响因子:
9.8
通讯作者:
Charlton, Jennifer R.
Charlton, Jennifer R.
中科院分区:
医学1区
文献类型:
--
作者:
Carmody, J. Bryan;Swanson, Jonathan R.;Charlton, Jennifer R.

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背景和目标 AKI 与短期发病率和死亡率增加以及 CKD 长期风险增加相关。本研究使用现代研究定义确定了极低出生体重婴儿中 AKI 的患病率,评估了出院小结中 AKI 诊断报告的频率,并确定婴儿是否被转介给儿科肾脏病专家进行 AKI 随访。设计、设置、参与者和测量对 2008 年至 2011 年入住 IV 级新生儿重症监护病房的极低出生体重婴儿的记录进行了审查。 AKI 使用肾脏疾病:改善全球结果定义进行分类,修改为仅包括血清肌酐。结果 455 名婴儿中,AKI 发生率为 39.8%; 75 名(16.5%)婴儿经历了多次 AM 发作,8 名(2%)婴儿因最后一次肌酐异常而出院。更新的婴儿临床风险指数评分 >10(比值比,12.9;95% 置信区间,7.8 至 21.4)和胎龄
Background and objectives AKI is associated with both increased short-term morbidity and mortality and greater long-term risk for CKD. This study determined the prevalence of AKI among very low birth weight infants using a modern study definition, evaluated the frequency of AKI diagnosis reporting in the discharge summary, and determined whether infants were referred to a pediatric nephrologist for AKI follow-up.Design, setting, participants, & measurements Records of very low birth weight infants admitted to a level IV neonatal intensive care unit from 2008 to 2011 were reviewed. AKI was classified using the Kidney Disease: Improving Global Outcomes definition modified to include only serum creatinine.Results AKI occurred in 39.8% of 455 infants; 75 (16.5%) infants experienced multiple episodes of AM, and 8 (2%) infants were discharged with an abnormal last creatinine. Updated clinical risk index for babies score >10 (odds ratio, 12.9; 95% confidence interval, 7.8 to 21.4) and gestational age