Internal carotid artery occlusion assessed at pulsed arterial spin-labeling perfusion MR imaging at multiple delay times
Internal carotid artery occlusion assessed at pulsed arterial spin-labeling perfusion MR imaging at multiple delay times
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DOI：
10.1148/radiol.2333031276
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发表时间：
2004-12-01
期刊：
影响因子：
19.7
通讯作者：
van der Grond, J
中科院分区：
文献类型：
--
作者：
Hendrikse, J;van Osch, MJP;van der Grond, J
采用脉冲动脉自旋标记（ASL）对9例颈内动脉（ICA）闭塞患者和11例对照组进行了6次不同倒置时间的磁共振（MR）成像。医院的人体科学研究委员会批准了这项研究方案，所有的研究对象都给予了知情同意。根据ASL在多次反转时测量的联合信号强度计算大脑中动脉区域的脑血流（CBF）。在ICA闭塞的患者中，与对侧半球灰质相比，闭塞的同侧半球灰质的平均CBF值降低（P< 0.05），与对照组的灰质值相比（P< 0.05）。用ASL在多次倒置时量化CBF可以补偿ICA闭塞患者的血液运输延迟。©rsna, 2004
Magnetic resonance (MR) imaging with pulsed arterial spin labeling (ASL) was performed at six different inversion times in nine patients with internal carotid artery (ICA) occlusion and in 11 control subjects. The hospital’s commission on scientific research on human subjects approved the study protocol, and all study subjects gave informed consent. Cerebral blood flow (CBF) in the middle cerebral artery territories was calculated from the combined signal intensities measured with ASL at the multiple inversion times. In the patients with ICA occlusion, mean CBF values were decreased in the gray matter of the hemisphere ipsilateral to the occlusion, as compared with values in the gray matter of the contralateral hemisphere (P< .05) and with values in the gray matter of the control subjects (P< .05). Quantification of CBF with ASL at multiple inversion times can compensate for the blood transit delays in patients with ICA occlusion.© RSNA, 2004