Guanacastepene-A total synthesis:: construction of the tricyclic iso-guanacastepane, epi-guanacastepane and guanacastepane frameworks
Guanacastepene-A total synthesis:: construction of the tricyclic iso-guanacastepane, epi-guanacastepane and guanacastepane frameworks
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DOI：
10.1016/s0040-4039(03)00883-9
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发表时间：
2003-05-26
影响因子：
1.8
通讯作者：
Srinivas, K
中科院分区：
文献类型：
--
作者：
Mehta, G;Umarye, JD;Srinivas, K
针对目前感兴趣的二萜抗生素guanacastepene A的全合成并显示出对耐药病原体的有希望的生物活性的研究已经导致产生了一些新的充满广泛官能化并代表guanacastepane框架的有趣变化的三环类化合物。(C)2003爱思唯尔科技有限公司版权所有。
Studies aimed towards the total synthesis of the diterpene antibiotic, guanacastepene A, of current interest and displaying promising biological activity against drug resistant pathogens has led to the generation of some novel tricyclic skeleta replete with extensive functionalization and representing interesting variations of the guanacastepane framework. (C) 2003 Elsevier Science Ltd. All rights reserved.