Monolithic polymer/carrier materials: Versatile composites for fine chemical synthesis
Monolithic polymer/carrier materials: Versatile composites for fine chemical synthesis
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DOI：
10.1016/j.cattod.2005.06.046
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发表时间：
2005-08-15
期刊：
影响因子：
5.3
通讯作者：
Turek, T
中科院分区：
文献类型：
--
作者：
Kunz, U;Kirschning, A;Turek, T
在我们的研究所开发的复合材料，理想地允许结合联合收割机用于有机合成的聚合物官能化与良好的整体载体的传质性能。从大孔玻璃载体材料开始，将聚合物引入该载体的孔体积中。在沉淀共聚过程中，形成小的聚合物球体，其通过聚合物桥连接，导致刚性聚合物整料侵入玻璃。这种独特的组合导致了用于有机合成的多功能材料，其可以以流通模式使用。基于这些具有不同聚合物官能度的整体材料，进行了多种不同的化学反应，例如选择性还原、Suzuki交叉偶联反应、亲核取代和催化转移加氢。这些反应用由不同尺寸的整体材料构造的反应器进行，从而允许实现从毫摩尔范围到几克的生产能力。(c)2005 Elsevier B.V.保留所有权利。
At our institutes composite materials were developed, which ideally allow to combine polymer functionalization utilized for organic synthesis with good mass transfer properties of monolithic carriers. Starting with a megaporous glass carrier material, a polymer is introduced into the pore volume of this support. During the precipitation co-polymerization small polymer spheres are formed, which are connected by polymer bridges, resulting in a rigid polymer monolith intruding the glass. This unique combination leads to versatile materials for organic synthesis, which can be used in a flow-through mode. Based on these monolithic materials with different polymer functionalities a wide variety of different chemical reactions was conducted such as selective reductions, Suzuki cross coupling reactions, nucleophilic substitutions and catalytic transfer hydrogenations. These reactions were performed with reactors constructed from monolithic materials of different sizes allowing to achieve production capacities ranging from the millimole range to several gramms. (c) 2005 Elsevier B.V. All rights reserved.