The Powdery Mildew Disease of Arabidopsis: A Paradigm for the Interaction between Plants and Biotrophic Fungi.
The Powdery Mildew Disease of Arabidopsis: A Paradigm for the Interaction between Plants and Biotrophic Fungi.
复制标题
DOI：
10.1199/tab.0115
复制
发表时间：
2008-01-01
期刊：
影响因子：
--
通讯作者：
Panstruga, Ralph
中科院分区：
文献类型：
--
作者：
Micali, Cristina;Gollner, Katharina;Panstruga, Ralph
白粉病是由丹毒属真菌引起的病害，对多种植物物种具有重要的经济影响，多年来一直是植物病理学基础研究和应用研究的热点。虽然关于丹毒真菌的第一批分类报告可以追溯到19世纪50年代，但这些真菌物种的分子生物学进展一直受到其特有的生物营养性质以及与实验室培养和遗传操作相关的困难的阻碍。20世纪90年代发现的几种引起拟南芥病害的白粉病真菌，开启了这一研究领域的新篇章。与模式植物物种合作的巨大优势已经转化为我们对这些复杂病原体及其与植物宿主相互作用的理解取得了显著进展。本文总结了拟南芥与白粉病相互作用的研究进展，并讨论了它们对植物病理学的一般意义。我们概述了拟南芥病原菌的生命周期，并描述了宿主和真菌在相容和不相容相互作用中感染过程中发生的结构和功能变化，特别强调了防御信号，抗性途径和相容性因子。最后，我们讨论了白粉病研究的未来，并对白粉病多基因组测序进行了展望。关于拟南芥白粉病的积累知识为研究和理解与许多其他专性生物营养病原体相关的疾病提供了有价值的工具。
The powdery mildew diseases, caused by fungal species of the Erysiphales, have an important economic impact on a variety of plant species and have driven basic and applied research efforts in the field of phytopathology for many years. Although the first taxonomic reports on the Erysiphales date back to the 1850's, advances into the molecular biology of these fungal species have been hampered by their obligate biotrophic nature and difficulties associated with their cultivation and genetic manipulation in the laboratory. The discovery in the 1990's of a few species of powdery mildew fungi that cause disease on Arabidopsis has opened a new chapter in this research field. The great advantages of working with a model plant species have translated into remarkable progress in our understanding of these complex pathogens and their interaction with the plant host. Herein we summarize advances in the study of Arabidopsis-powdery mildew interactions and discuss their implications for the general field of plant pathology. We provide an overview of the life cycle of the pathogens on Arabidopsis and describe the structural and functional changes that occur during infection in the host and fungus in compatible and incompatible interactions, with special emphasis on defense signaling, resistance pathways, and compatibility factors. Finally, we discuss the future of powdery mildew research in anticipation of the sequencing of multiple powdery mildew genomes. The cumulative body of knowledge on powdery mildews of Arabidopsis provides a valuable tool for the study and understanding of disease associated with many other obligate biotrophic pathogen species.