Differences between motor point and innervation zone locations in the biceps brachii. An exploratory consideration for the treatment of spasticity with botulinum toxin
Differences between motor point and innervation zone locations in the biceps brachii. An exploratory consideration for the treatment of spasticity with botulinum toxin
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DOI：
10.1016/j.jelekin.2014.07.012
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发表时间：
2014-12-01
影响因子：
2.5
通讯作者：
Silvestre, Rony A.
中科院分区：
文献类型：
--
作者：
Guzman-Venegas, Rodrigo A.;Araneda, Oscar F.;Silvestre, Rony A.
背景：肉毒毒素（BTX）作用于神经肌肉接头，而神经肌肉接头可由神经支配带（IZ）定位。临床上，运动点（MP）与IZ同源，并被用作BTX的注射部位。已确定MP和IZ位置之间应用BTX的有效性差异。目的：比较使用电刺激获得的MP位置和使用肱二头肌上的线性表面电极阵列获得的IZ位置。方法：评估二十名男性的肱二头肌。使用电刺激产生的扭矩测量值定位MP。IZ使用线性表面电极阵列检测。结果：MP和IZ位置之间的差异（75.8与86.5 mm，Δ 10.7 mm; p = 0.003，事后功率0.89）observed.Discussion：MP和IZ之间的差异幅度可能与临床相关。IZ的位置使用表面肌电图作为指导，以优化BTX注射建议。(C)2014爱思唯尔有限公司版权所有。
Background: Botulinum toxin (BTX) acts on the neuromuscular junction which can be located by the innervation zone (IZ). Clinically, the motor point (MP) is homologous to the IZ and it is used as the injection site of BTX. Differences in the effectiveness of the application of BTX between MP and IZ locations have been determined.Objective: Compare the location of the MP obtained using electrical stimulation and the location of the IZ using a linear surface electrodes array on the biceps brachii muscle.Methods: The biceps brachii muscle of twenty men was assessed. The MP was located using the torque measurement generated by electrical stimulation. The IZ was detected using a linear surface electrodes array.Results: A difference between the MP and the IZ positions (75.8 vs. 86.5 mm, delta 10.7 mm; p = 0.003, post-hoc power 0.89) was observed.Discussion: The magnitude of the difference between the MP and the IZ may be clinically relevant. The IZ location using surface electromyography as a guide to optimize BTX injection is proposed. (C) 2014 Elsevier Ltd. All rights reserved.