Zoo animals as reservoirs of gram-negative bacteria harboring integrons and antimicrobial resistance genes
Zoo animals as reservoirs of gram-negative bacteria harboring integrons and antimicrobial resistance genes
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DOI：
10.1128/aem.01054-07
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发表时间：
2007-10-01
影响因子：
4.4
通讯作者：
Shimamoto, Tadashi
中科院分区：
文献类型：
--
作者：
Ahmed, Ashraf M.;Motoi, Yusuke;Shimamoto, Tadashi
从日本广岛县阿萨动物园饲养的哺乳动物、爬行动物和鸟类中共回收了232株革兰氏阴性菌。49株（21.1%）具有多重耐药表型，并携带至少一种抗菌药物耐药基因。PCR和DNA测序鉴定了I类和2类整合子和许多P-内酰胺酶编码基因，以及一个新的AmpC P-内酰胺酶基因bla（CMY-26）。此外，还鉴定了质粒介导的喹诺酮类耐药基因qnr和aac（6 '）-Ib-cr。
A total of 232 isolates of gram-negative bacteria were recovered from mammals, reptiles, and birds housed at Asa Zoological Park, Hiroshima prefecture, Japan. Forty-nine isolates (21.1%) showed multidrug resistance phenotypes and harbored at least one antimicrobial resistance gene. PCR and DNA sequencing identified class I and class 2 integrons and many P-lactamase-encoding genes, in addition to a novel AmpC P-lactamase gene, bla(CMY-26). Furthermore, the plasmid-mediated quinolone resistance genes qnr and aac(6')-Ib-cr were also identified.