INCIDENCE OF METHANOGENIC BACTERIA IN A SIGMOIDOSCOPY POPULATION - AN ASSOCIATION OF METHANOGENIC BACTERIA AND DIVERTICULOSIS
INCIDENCE OF METHANOGENIC BACTERIA IN A SIGMOIDOSCOPY POPULATION - AN ASSOCIATION OF METHANOGENIC BACTERIA AND DIVERTICULOSIS
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DOI：
10.1136/gut.27.6.698
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发表时间：
1986-06-01
期刊：
影响因子：
24.5
通讯作者：
WOLIN, MJ
中科院分区：
文献类型：
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作者：
WEAVER, GA;KRAUSE, JA;WOLIN, MJ
本研究测定了130例乙状结肠镜检查前自来水灌肠标本中产甲烷细菌的发生率和浓度。研究对象分为五个主要的结肠组：正常结肠36例，憩室病57例，炎症性肠病11例，结肠息肉34例，结肠癌11例。有些患者被归入多个类别。94名受试者或72%的受试者粪便中产甲烷细菌的浓度由6至约3×10(10)/克干重不等。各组产甲烷菌以史密斯甲烷短杆菌为主。卡方分析显示，憩室病患者粪便中10(7)个/g干重或以上的甲烷菌的发生率(58%)显著高于正常组(25%)。甲烷浓度高与呼气中甲烷的排泄有关。
This study determined the incidence and concentration of methane-producing bacteria in tap water enema samples of 130 individuals taken before sigmoidoscopy. The number of subjects classified in five major colonic groups were as follows: normal colon 36, diverticulosis 57, inflammatory bowel disease 11, colon polyps 34, and colon cancer 11. Some patients were placed in more than one category. Ninety four of the subjects or 72% had methanogenic bacteria ranging in concentration from 6 to about 3 X 10(10)/g dry weight of faeces. The predominant methanogen in all groups was Methanobrevibacter smithii. Chi-square analysis showed that the incidence of methanogens in concentrations of 10(7)/g dry weight of faeces or greater in patients with diverticulosis (58%) was significantly greater than in normal patients (25%). High methanogen concentrations are associated with excretion of methane in the breath.