Michael addition of poly-L-lysine to N-acryloylated sialosides. Syntheses of influenza A virus haemagglutinin inhibitor and group B meningococcal polysaccharide vaccinest
Michael addition of poly-L-lysine to N-acryloylated sialosides. Syntheses of influenza A virus haemagglutinin inhibitor and group B meningococcal polysaccharide vaccinest
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Michael 将聚-L-赖氨酸加成至 N-丙烯酰化唾液酸苷上。
DOI：
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发表时间：
1993
期刊：
影响因子：
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通讯作者：
F. Andersson
中科院分区：
文献类型：
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作者：
R. Roy;R. Pon;F. Tropper;F. Andersson
N-丙烯酰化唾液酸糖苷衍生物通过其NIµ-赖氨酸残基的1，4-缀合物加成直接缀合至聚-L-赖氨酸和蛋白质载体，以提供具有潜在治疗效用的新糖缀合物。
N-Acryloylated sialoside derivatives are directly conjugated to poly-L-lysine and protein carriers by the 1,4-conjugate additions of their NIµ-lysine residues to provide new glycoconjugates with potential therapeutic utilities.