Relationship of metabolic syndrome to periodontal disease in Japanese women: The Hisayama study

Relationship of metabolic syndrome to periodontal disease in Japanese women: The Hisayama study
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DOI:
10.1177/154405910708600314
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发表时间:
2007-03-01
影响因子:
7.6
通讯作者:
Yamashita, Y.
Yamashita, Y.
中科院分区:
医学1区
文献类型:
--
作者:
Shimazaki, Y.;Saito, T.;Yamashita, Y.

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最近的研究表明,一些全身性疾病,如肥胖、高血压、高脂血症和糖尿病,都与牙周炎有关。本研究的目的是研究牙周炎与584名日本女性代谢综合征的5个组成部分——腹部肥胖、甘油三酯水平、高密度脂蛋白胆固醇水平、血压和空腹血糖水平之间的关系。在多变量分析中,表现出更多代谢综合征成分的人比那些没有代谢综合征成分的人有更高的口袋深度和临床附着丧失的比值比;表现出4种或5种成分的患者的口袋深度和临床附着丧失的比值比分别为6.6(95%可信区间= 2.6-16.4)和4.2(95%可信区间= 1.2-14.8)。这些结果表明,代谢综合征增加牙周炎的风险,并建议表现出代谢综合征的几个组成部分的人应鼓励进行牙周检查。
Recent studies have suggested that several systemic conditions-such as obesity, hypertension, hyperlipidemia, and diabetes-are related to periodontitis. The objective of this study was to examine the relationship between periodontitis and 5 components of metabolic syndrome-abdominal obesity, triglyceride level, high-density lipoprotein cholesterol level, blood pressure, and fasting blood sugar level-in 584 Japanese women. In multivariate analyses, persons exhibiting more components of metabolic syndrome had significantly higher odds ratios for a greater pocket depth and clinical attachment loss than did those with no components; the odds ratios for a greater pocket depth and clinical attachment loss of the persons exhibiting 4 or 5 components were 6.6 (95% confidence interval = 2.6-16.4) and 4.2 (95% confidence interval = 1.2-14.8), respectively. These results indicate that metabolic syndrome increases risk of periodontitis, and suggest that people exhibiting several components of metabolic syndrome should be encouraged to undergo a periodontal examination.