Referential communication in Alzheimer's type dementia
Referential communication in Alzheimer's type dementia
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DOI：
10.1016/s0010-9452(08)70192-8
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发表时间：
2005-08-01
期刊：
影响因子：
3.6
通讯作者：
Marini, A
中科院分区：
文献类型：
--
作者：
Carlomagno, S;Santoro, A;Marini, A
本文探讨了阿尔茨海默型痴呆（DAT）患者话语中信息量减少和缺乏参考的因素。DAT患者，流利的失语症和正常对照组被给予一个参照沟通任务，结构化评估词汇编码的信息，语用/概念阐述的信息和有效性，建立参考。受试者还接受了标准化的失语症测试（CADL，Holland，1980;以及Cookie盗窃图片描述，Nicholas和布鲁克郡，1993）。在失语症和DAT参与者的话语中，无论是在参考沟通任务的措施和标准化的评价与Cookie盗窃图片描述测试的词汇编码的信息被发现相当的减少。然而，白天被试在指称交际任务中的话语建立指称的效率低于失语症被试，因为前者表现出更多的误解，需要听者更明确的提示。此外，在指称交际任务中，DAT语言中含有混杂和无关信息，这些错误的数量与他们的指称能力呈负相关。CADL测试的结果证实，DAT参与者的交际效果比他们的词汇缺陷单独预测。最后，对个别DAT被试的测试结果表明，信息的词汇编码与指称的有效性无关，这些结果支持了这样一种观点，即语篇信息内容的语用/概念阐述困难在DAT“空语”的信息内容减少和指称缺乏的发展中起着重要作用。这些结果在DAT中的早期注意/执行损伤的假设的框架下进行了讨论（佩里和霍奇斯，1999）。
This paper investigates factors that underlie reduced informative content and lack of reference in the discourse of patients with Alzheimer's Type Dementia (DAT). Patients with DAT, fluent aphasics and normal controls were given a referential communication task structured to assess lexical encoding of information, pragmatic/conceptual elaboration of information and effectiveness in establishing reference. The subjects also received standardised aphasia tests (CADL, Holland, 1980; and Cookie Theft Picture Description, Nicholas and Brookshire, 1993). Comparable reduction of lexical encoding of information was found in the discourse of aphasic and DAT participants both on the referential communication task measures and on the standardised evaluation with the Cookie Theft Picture Description test. However, the DAY subjects' discourse on the referential communication task was less efficient in establishing reference than that of the aphasics since the former presented more misunderstandings and required more explicit prompts from the listener. Furthermore, the DAT language on the referential communication task contained confounding and irrelevant information; also, the number of these errors correlated negatively with their referring abilities. Results of the CADL test confirmed that the DAT participants had less communicative effectiveness than their lexical deficit alone predicted. Finally, examination of the performance of individual DAT subjects showed that lexical encoding of information could dissociate from effectiveness in making reference.These findings support the view that difficulty in pragmatic/conceptual elaboration of discourse information content plays a substantial role in the development of reduced information content and lack of reference of DAT "empty speech". These results are discussed in the framework of the hypothesis of early attentional/executive impairment in DAT (Perry and Hodges, 1999).