Increased pain catastrophizing longitudinally predicts worsened pain severity and interference in patients with chronic pain and cancer: A collaborative health outcomes information registry study (CHOIR).
Increased pain catastrophizing longitudinally predicts worsened pain severity and interference in patients with chronic pain and cancer: A collaborative health outcomes information registry study (CHOIR).
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DOI：
10.1002/pon.6020
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发表时间：
2022-10
期刊：
影响因子：
3.6
通讯作者：
Azizoddin, Desiree R.
中科院分区：
文献类型：
--
作者：
Wilson, Jenna M.;Schreiber, Kristin L.;Mackey, Sean;Flowers, K. Mikayla;Darnall, Beth D.;Edwards, Robert R.;Azizoddin, Desiree R.
关键词：
人们对心理社会因素的变化如何影响癌症和慢性疼痛患者疼痛结果的变化知之甚少。这项针对癌症患者的纵向队列研究调查了心理社会因素的变化与疼痛严重程度和干扰随时间的变化之间的关系。前瞻性收集了在三级疼痛诊所接受治疗的癌症和慢性疼痛患者 (n = 316) 的数据。在基线访视（时间 1）时，患者提供了人口统计和临床信息，并完成了经过验证的心理社会和疼痛评估。平均 4.9 个月后，在随访（时间 2）时重复进行心理社会和疼痛评估。计算社会心理和疼痛变量的变化分数（时间2-时间1）。多变量分层线性回归评估了心理社会因素的变化与疼痛结果随时间的变化之间的关联。参与者平均年龄 59 岁，其中 61% 为女性，69% 为白人。总体而言，随着时间的推移，观察到该组患者的疼痛严重程度有所下降（p ≤ 0.001），但疼痛干扰并未减少。在多变量分析中，随着时间的推移，疼痛灾难化程度的增加与疼痛严重程度的增加显着相关（β = 0.24，p ≤ 0.001）。同样，随着时间的推移，疼痛灾难化程度的增加（β = 0.21，p ≤ 0.001）和抑郁程度的增加（β = 0.20，p ≤ 0.003）与疼痛干扰的增加显着相关。人口统计学和临床特征与疼痛结果的变化没有显着相关。疼痛灾难化的增加与慢性疼痛严重程度和干扰的增加有着独特的相关性。我们的研究结果表明，患有慢性疼痛的癌症患者可能会受益于非药物干预措施的结合，同时解决疼痛和心理症状。
Little is known about how changes in psychosocial factors impact changes in pain outcomes among patients with cancer and chronic pain. This longitudinal cohort study of cancer patients investigated the relationships between changes in psychosocial factors and changes in pain severity and interference over time. Data from patients with cancer and chronic pain (n = 316) treated at a tertiary pain clinic were prospectively collected. At their baseline visit (Time 1), patients provided demographic and clinical information, and completed validated psychosocial and pain assessments. Psychosocial and pain assessments were repeated at a follow-up visit (Time 2), on average 4.9 months later. Change scores (Time 2-Time 1) were computed for psychosocial and pain variables. Multivariable hierarchical linear regressions assessed the associations between changes in psychosocial factors with changes in pain outcomes over time. Participants were an average age of 59 years, were 61% female, and 69% White. Overall, a decrease in pain severity (p ≤ 0.001), but not pain interference, was observed among the group over time. In multivariable analyses, increased pain catastrophizing was significantly associated with increased pain severity over time (β = 0.24, p ≤ 0.001). Similarly, increased pain catastrophizing (β = 0.21, p ≤ 0.001) and increased depression (β = 0.20, p ≤ 0.003) were significantly associated with increased pain interference over time. Demographic and clinical characteristics were not significantly related to changes in pain outcomes. Increased pain catastrophizing was uniquely associated with increased chronic pain severity and interference. Our findings indicate that cancer patients with chronic pain would likely benefit from the incorporation of nonpharmacological interventions, simultaneously addressing pain and psychological symptoms.
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影响因子：
2.7
作者：
Darnall BD;Sturgeon JA;Kao MC;Hah JM;Mackey SC
通讯作者：
Mackey SC
影响因子：
13.8
作者：
Darnall BD;Roy A;Chen AL;Ziadni MS;Keane RT;You DS;Slater K;Poupore-King H;Mackey I;Kao MC;Cook KF;Lorig K;Zhang D;Hong J;Tian L;Mackey SC
通讯作者：
Mackey SC
影响因子：
3.6
作者：
Luigjes-Huizer, Yvonne L.;Tauber, Nina M.;Humphris, Gerry;Kasparian, Nadine A.;Lam, Wendy W. T.;Lebel, Sophie;Simard, Sebastien;Smith, Allan Ben;Zachariae, Robert;Afiyanti, Yati;Bell, Katy J. L.;Custers, Jose A. E.;de Wit, Niek J.;Fisher, Peter L.;Galica, Jacqueline;Garland, Sheila N.;Helsper, Charles W.;Jeppesen, Mette M.;Liu, Jianlin;Mititelu, Roxana;Monninkhof, Evelyn M.;Russell, Lahiru;Savard, Josee;Speckens, Anne E. M.;van Helmondt, Sanne J.;Vatandoust, Sina;Zdenkowski, Nicholas;van der Lee, Marije L.
通讯作者：
van der Lee, Marije L.
影响因子：
6.2
作者：
Azizoddin, Desiree R.;Schreiber, Kristin;Beck, Meghan R.;Enzinger, Andrea C.;Hruschak, Valerie;Darnall, Beth D.;Edwards, Robert R.;Allsop, Matthew J.;Tulsky, James A.;Boyer, Edward;Mackey, Sean
通讯作者：
Mackey, Sean
影响因子：
6.3
作者：
Shah, Rahul;Chou, Lin-Na;Raji, Mukaila A.
通讯作者：
Raji, Mukaila A.