Behavioral state and plasma cortisol response in the human newborn.

Behavioral state and plasma cortisol response in the human newborn.
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人类新生儿的行为状态和血浆皮质醇反应。

DOI:
10.1542/peds.46.4.532
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发表时间:
1970
期刊:
影响因子:
8
通讯作者:
Leon Hellman
Leon Hellman
中科院分区:
医学2区
文献类型:
--
作者:
Thomas F. Anders;Edward J. Sachar;Jacob Kream;H. Roffwarg;Leon Hellman

文献摘要

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对四名正常人类婴儿在出生后第一周至第十五周期间进行了 20 次研究,以评估四种行为状态(哭泣、安静清醒、快速眼动睡眠和非快速眼动睡眠)与血浆皮质醇水平的关系。哭泣 20 分钟后血浆皮质醇显着升高。在其他行为状态下,血浆皮质醇保持较低水平且相对稳定。该模式不随年龄而改变,并且在本研究的限制范围内,没有证明昼夜节律。有人建议,血浆皮质醇的测量在婴儿期心理生理学研究中的作用与已被证明在成人中的作用一样有用。
Four normal human infants were studied on 20 occasions between the first and fifteenth week of their life to assess the relation of four behavioral states (crying, quiet wakefulness, rapid eye movement, and non-rapid eye movement sleep) to plasma cortisol levels. Marked rises in plasma cortisol occurred after 20 minutes of crying. In the other behavioral states, plasma cortisol remained low and relatively constant. The pattern did not change with age, and within the limitations of this study no circadian rhythm was demonstrated. It is suggested that measurement of plasma cortisol can be as useful in psychophysiological investigations in infancy as it has proved to be in the adult.